W1-ALS1 ATP production Flashcards
oxidative phosphorylation location
inner mitochondrial membrane
what happens during OP
reoxidation of NADH and FADH2
inheritance of MtDNA
through the ovum, therefore affecting maternal offsprings
frequent cause of genetic disease
endosymbiotic theory
arise from preexisting own genome of circular DNA own protein synthesis machinery formulated methionine production similar response to antibiotics as prokaryotes
ETC
3 enzymes- NADH dehydrogenase complex 1, cytochrome b-1c complex and cytochromes oxidase complex
2 carrier- cytochrome C and ubiquinone
extra enzyme succinate dehydorgenase
redox
oxidation and reduction reaction
redox potential
ability to be either oxidised or reduced easier
redox couple
ability to be both oxidised and reduced
more negative E0 implies
more oxidised as give electrons away
less negative E0 implies
more reduced as accept electrons easier
ATP synthase
F0- inside membrane bound part
F1- protrude into the matrix
direction of flow of protons
H+ in means synthesis
H- out means breakdown
oxygen electrode
Pt cathode and Ag anode
current proportional to oxygen concentration in chamber
respiratory control
inorganic phosphate and ADP
body adapt oxygen consumption to energy requirement
metabolic poisons
cyanide and azide malonate rotenone oligomycin DNP
