W/L Ch 1 Cancer: An Overview Quiz Flashcards

1
Q

Knowledge of cancer dates back to which of the following?

a. 1600 BC Egypt
b. 1600 AD England
c. 400 BC Greece
d. 1900 AD Germany

A

a. 1600 BC Egypt

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2
Q

Which of the following is not a term for genes involved in the cancer process?

a. Anti-oncogenes
b. Oncogenes
c. Proto-oncogenes
d. Somato-oncogenes

A

d. Somato-oncogenes

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3
Q

Tumor-suppressor genes are also known as ___________.

a. anti-oncogenes
b. oncogenes
c. proto-oncogenes
d. somato-oncogenes

A

a. anti-oncogenes

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4
Q

Which of the following is not a phase of the mammalian cell cycle?

a. G0
b. G1
c. G2
d. G3

A

d. G3

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5
Q

Which phase of the mammalian cell cycle is composed of functional cells not preparing for DNA replication?

a. G0
b. G1
c. G2
d. S
e. M

A

a. G0

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6
Q

In which phase of the mammalian cell cycle does DNA synthesis occur?

a. G0
b. G1
c. G2
d. S
e. M

A

d. S

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7
Q

Identify the correct order for the phases of the mammalian cell cycle.

a. G1, G2, M, S
b. G1, G2, S, M
c. G1, M, G2, S
d. G1, S, G2, M

A

d. G1, S, G2, M

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8
Q

Which of the following is true of anaplastic tumors?

a. Closely resemble the cells of origin
b. Maintain some resemblance of the cells of origin
c. Do not resemble the cells of origin

A

c. Do not resemble the cells of origin

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9
Q

Which of the following is (are) true of benign tumors?

a. Well differentiated
b. Do not metastasize
c. Encapsulated
d. All of the above

A

d. All of the above

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10
Q

Which of the following factors does not affect the incidence of tumor sites?

a. Informational
b. Environmental
c. Technological
d. Geographic

A

a. Informational

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11
Q

What is defined as the “study of the cause of disease”?

a. Etiology
b. Etymology
c. Epidemiology
d. Entomology

A

a. Etiology

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12
Q

What is the “study of disease incidence”?

a. Etiology
b. Etymology
c. Epidemiology
d. Entomology

A

c. Epidemiology

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13
Q

Which of the following make(s) for an effective screening examination?

a. Specific
b. Sensitive
c. Cost-effective
d. Accurate
e. All of the above

A

e. All of the above

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14
Q

What is the “workup”?

a. The initial nursing visit
b. The initial physician visit
c. A series of diagnostic examinations
d. A physical assessment of the patient

A

c. A series of diagnostic examinations

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15
Q

Which of the following is not typically part of the workup?

a. Patient demographics
b. Type, location, and size of tumor
c. Normal tissue invasion
d. Presence of metastases

A

a. Patient demographics

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16
Q

Which imaging modality is beneficial for distinguishing between recurrent disease and other tissue changes post treatment?

a. CT
b. PET
c. Plain films
d. MR

A

b. PET

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17
Q

What is the most common tumor staging system?

a. AJCC
b. FIGO
c. TNM
d. UICC

A

c. TNM

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18
Q

A T1N0MX tumor has how many positive lymph nodes?

a. 0
b. 1
c. 2
d. Unknown

A

a. 0

19
Q

Tumors are the result of which of the following?

a. Black bile
b. Necrotic tissue
c. Abnormal cellular proliferation
d. Traumatic injury

A

c. Abnormal cellular proliferation

20
Q
Tumor grade is a measure of \_\_\_\_\_\_\_\_.
I.   aggressiveness
II.  differentiation
III. spread
a.	I and II
b.	I and III
c.	II and III
d.	I, II, and III
A

a. I and II

21
Q

Which of the following biopsy methods results in the removal of the entire tumor?

a. Fine needle aspiration
b. Core needle
c. Incisional
d. Excisional

A

d. Excisional

22
Q

Which of the following biopsy methods cannot evaluate tumor architecture?

a. Fine needle aspiration
b. Core needle
c. Incisional
d. Excisional

A

a. Fine needle aspiration

23
Q

Factors that may exclude a patient from having surgery include all except which of the following?

a. Preexisting medical conditions
b. Tumor location
c. Patient preference
d. Classification

A

d. Classification

24
Q

When compared with surgery, benefits of radiation therapy include all except which of the following?

a. Instantaneous cure
b. Better cosmetic results
c. Preservation of function
d. Noninvasive

A

a. Instantaneous cure

25
Q

Which of the following treatment techniques uses radioactive sources?

a. External beam
b. Intraoperative
c. Brachytherapy
d. IMRT

A

c. Brachytherapy

26
Q

Which of the following is not used for brachytherapy treatments?

a. Cesium
b. Cobalt
c. Iodine
d. Iridium

A

b. Cobalt

27
Q

High-dose after loading equipment is used in association with which treatment technique?

a. External beam
b. Intraoperative
c. Brachytherapy
d. IMRT

A

c. Brachytherapy

28
Q

Pancreatic cancer may be treated using which technique?

a. Intraluminal
b. Intravascular
c. Intracavitary
d. Intraoperative

A

d. Intraoperative

29
Q

Which of the following is a systemic treatment?

a. Surgery
b. Radiation therapy
c. Chemotherapy
d. All of the above

A

c. Chemotherapy

30
Q

Which of the following routes of administration is used when treating bladder cancer with chemotherapy?

a. Oral
b. Intra-arterial
c. Intracavitary
d. Intrathecal

A

c. Intracavitary

31
Q

Which classification of chemotherapy agents was the first to be identified as having anticancer activities?

a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids

A

a. Alkylating agents

32
Q
Which of the following are not cell cycles specific?
I.   Alkylating agents
II.  Antimetabolites
III. Antibiotics
IV. Hormonal agents
V.  Nitrosoureas
VI. Vinca alkaloids
a.	I and II
b.	I and III
c.	I, III, and V
d.	II, IV, and VI
e.	II, III, and VI
A

c. I, III, and V

33
Q

Which classification of chemotherapy agents is derived from the periwinkle plant?

a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids

A

f. Vinca alkaloids

34
Q

In which classification are the chemotherapy agent’s lipids soluble and capable of crossing the blood-brain barrier?

a. Alkylating agents
b. Antimetabolites
c. Antibiotics
d. Hormonal agents
e. Nitrosoureas
f. Vinca alkaloids

A

e. Nitrosoureas

35
Q

Which of the following is a radiosensitizing chemotherapy agent?

a. Cyclophosphamide
b. 5-Fluorouracil
c. Doxorubicin
d. Cisplatin

A

c. Doxorubicin

36
Q

Which of the following acts as a radioprotector?

a. Amifostine
b. Actinomycin D
c. Adriamycin
d. Etoposide

A

a. Amifostine

37
Q

Injecting monoclonal antibodies is an example of which type of treatment?

a. Surgery
b. Radiation therapy
c. Chemotherapy
d. Immunotherapy

A

d. Immunotherapy

38
Q

Which of the following best describes tumor spread?

a. Exophytic
b. Multicentric
c. Dissemination
d. Ulceration

A

c. Dissemination

39
Q

Which of the following factors is not considered when determining a prognosis?

a. Tumor stage
b. Nodal status
c. Gender
d. All are considered

A

d. All are considered

40
Q

Randomized studies are, by definition, which phase?

a. I
b. II
c. III
d. IV

A

c. III

41
Q

Which staff member is most responsible for designing the patient’s treatment plan?

a. Medical physicist
b. Radiation oncologist
c. Dosimetrist
d. Radiation therapist

A

c. Dosimetrist

42
Q

Which staff member is most responsible for the quality assurance to the treatment equipment?

a. Medical physicist
b. Radiation oncologist
c. Dosimetrist
d. Radiation therapist

A

a. Medical physicist

43
Q

Which of the following is an example of an etiologic factor?

a. Gender
b. Sex
c. Race
d. Social habits

A

d. Social habits

44
Q

A cancer designated with an N1 classification using the TNM staging system likely indicates which of the following?

a. No positive lymph nodes are involved.
b. Positive lymph nodes are involved at distant sites.
c. Positive lymph nodes are involved near the site.
d. Lymph nodes cannot be accessed.

A

c. Positive lymph nodes are involved near the site.