Mosby Ch 2 An Overview of Cancer and Management Modalities Flashcards

1
Q

Benign Tumors (8)

A
  1. Encapsulated
  2. rerely fatal
  3. Little effect on the host
  4. Differentiated
  5. Slow growth
  6. low mitotic activity
  7. Little tissue destruction
  8. Abnormal proliferatio of cells
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2
Q

Malignant Tumors (9):

A
  1. Unencapsulated
  2. Potentially fatal
  3. Substantial effect on the host
  4. Differentiated to undifferentiated
  5. Rapid growth
  6. high mitotic activity
  7. Potentially metastatic
  8. Invasive and destructiove to tissue
  9. abnormal proiferation of cells
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3
Q

Cancer screening recommendations from ACS for men (5):

A
  1. Colonoscopy beginning at age 50, annual or longer interval if low risk.
  2. Fecal Occult Blood test, “ “.
  3. Manual testicular exam beginning at late adolescence, annual
  4. Digital retal examination beginning at age 45, annual
  5. PSA beginning at age 50, annual, earlier if family history
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4
Q

Cancer screening recommendations from ACS for women (5):

A
  1. Manual breast examination beginning at late adolescence, monthly; or each GYN visit
  2. Pelvic exam and pap smear beginning at the time of sexual activity
  3. Mammogram, baseline at age 40 or earlier if family history; annually thereafter
  4. Colonoscopy beginning at age 50, annual or longer interval if low risk.
  5. Fecal Occult Blood test, “ “.
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5
Q

Curettage or exfoliation

A

scraping of cells

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6
Q

Excisional biopsy

A

complete removal of suspicious tissue and margins

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7
Q

Incisional biopsy

A

cutting into and taking a portion of suspicious tissue

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8
Q

Fine needle aspiration (FNA)

A

use of a needle and syringe to draw out fluid and suspicious tissue

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9
Q

Core biopsy

A

use of large bore needle to withdraw a section of tissue

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10
Q

Sputum cytology

A

sampling of sputum

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11
Q

Washing or irrigation

A

introduction of saline into a cavity and analysis of returned solution containign cells

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12
Q

Open biopsy

A

surgical proceudre exposing area of suspicious tissue for the visual investigation of local area

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13
Q

_______ is a malignancy originating in glial tissue.

A

Glioma

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14
Q

Basal cell, Squamous Cell, Adenocarcinoma originate in _______ tissue.

A

epithelial

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15
Q

_______ are for management of nausea and vomiting.

A

Antimetics

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16
Q

Cytotoxic drugs, Antitumor drugs, and Chemotherapy drugs are used for the management of ______.

A

cancer

17
Q

______ is a hormonal agent.

A

Tamoxifen

18
Q

5-FU, Methotrexate and Purinethol are _________.

A

cytotoxic

19
Q

Used to prevent the future manifestation of cancer in a location with no declared disease but possibly microscopic disease not yet detectable. It sterilizes the potential area of mets disease

A

Prophylactic management

20
Q
Malignant tumor of glandular epithelium
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f. Glioma
A

b. Adenocarcinoma

21
Q
Abnormal proliferation occuring in the bone marrow
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f. Glioma
A

a. Myeloma

22
Q
Abnormal proliferation occuring in the bone marrow, especially the white blood cells. 
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f. Glioma
A

d. Leukemia

23
Q
Malignant tumor occuring in the bone
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f.Glioma
A

c. Osteosarcoma

24
Q
Malignant tumor occurring in striated muscle
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f Glioma
A

e. Rabdomyosarcoma

25
Q
Malignant tumor originating in the CNS
a. Myeloma
b. Adenocarcinoma
c. Osteosarcoma
d Leukemia
e. Rabdomyosarcoma
f Glioma
A

f. Glioma

26
Q

Effective on dividing cells

a. Phase specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

a. Phase specific cytotoxic drugs

27
Q

Effective on non dividing cells

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

b. Phase non-specific cytotoxic drugs

28
Q

One such class would be Antimetabolites

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

a. Phase spacific cytotoxic drugs

29
Q

One class would be alkylating agents

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

b. Phase non-specific cytotoxic drugs

30
Q

Examples are 5-FU, cytarabine, floxuridine, 6-mercaptopurine

a. Phase specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

a. Phase specific cytotoxic drugs

31
Q

Examples are Nitrogen mustard, cisplatin, cyclophosphaide

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

b. Phase non-specific cytotoxic drugs

32
Q

Toxicities include myelosuppression, anorexia, nausea

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

a. Phase spacific cytotoxic drugs

33
Q

Toxicities include myelosupression kidney toxicity, nause anorexia, neurotoxicity

a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs

A

b. Phase non-specific cytotoxic drugs