Mosby Ch 2 An Overview of Cancer and Management Modalities Flashcards
Benign Tumors (8)
- Encapsulated
- rerely fatal
- Little effect on the host
- Differentiated
- Slow growth
- low mitotic activity
- Little tissue destruction
- Abnormal proliferatio of cells
Malignant Tumors (9):
- Unencapsulated
- Potentially fatal
- Substantial effect on the host
- Differentiated to undifferentiated
- Rapid growth
- high mitotic activity
- Potentially metastatic
- Invasive and destructiove to tissue
- abnormal proiferation of cells
Cancer screening recommendations from ACS for men (5):
- Colonoscopy beginning at age 50, annual or longer interval if low risk.
- Fecal Occult Blood test, “ “.
- Manual testicular exam beginning at late adolescence, annual
- Digital retal examination beginning at age 45, annual
- PSA beginning at age 50, annual, earlier if family history
Cancer screening recommendations from ACS for women (5):
- Manual breast examination beginning at late adolescence, monthly; or each GYN visit
- Pelvic exam and pap smear beginning at the time of sexual activity
- Mammogram, baseline at age 40 or earlier if family history; annually thereafter
- Colonoscopy beginning at age 50, annual or longer interval if low risk.
- Fecal Occult Blood test, “ “.
Curettage or exfoliation
scraping of cells
Excisional biopsy
complete removal of suspicious tissue and margins
Incisional biopsy
cutting into and taking a portion of suspicious tissue
Fine needle aspiration (FNA)
use of a needle and syringe to draw out fluid and suspicious tissue
Core biopsy
use of large bore needle to withdraw a section of tissue
Sputum cytology
sampling of sputum
Washing or irrigation
introduction of saline into a cavity and analysis of returned solution containign cells
Open biopsy
surgical proceudre exposing area of suspicious tissue for the visual investigation of local area
_______ is a malignancy originating in glial tissue.
Glioma
Basal cell, Squamous Cell, Adenocarcinoma originate in _______ tissue.
epithelial
_______ are for management of nausea and vomiting.
Antimetics
Cytotoxic drugs, Antitumor drugs, and Chemotherapy drugs are used for the management of ______.
cancer
______ is a hormonal agent.
Tamoxifen
5-FU, Methotrexate and Purinethol are _________.
cytotoxic
Used to prevent the future manifestation of cancer in a location with no declared disease but possibly microscopic disease not yet detectable. It sterilizes the potential area of mets disease
Prophylactic management
Malignant tumor of glandular epithelium a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f. Glioma
b. Adenocarcinoma
Abnormal proliferation occuring in the bone marrow a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f. Glioma
a. Myeloma
Abnormal proliferation occuring in the bone marrow, especially the white blood cells. a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f. Glioma
d. Leukemia
Malignant tumor occuring in the bone a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f.Glioma
c. Osteosarcoma
Malignant tumor occurring in striated muscle a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f Glioma
e. Rabdomyosarcoma
Malignant tumor originating in the CNS a. Myeloma b. Adenocarcinoma c. Osteosarcoma d Leukemia e. Rabdomyosarcoma f Glioma
f. Glioma
Effective on dividing cells
a. Phase specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
a. Phase specific cytotoxic drugs
Effective on non dividing cells
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
One such class would be Antimetabolites
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
a. Phase spacific cytotoxic drugs
One class would be alkylating agents
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
Examples are 5-FU, cytarabine, floxuridine, 6-mercaptopurine
a. Phase specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
a. Phase specific cytotoxic drugs
Examples are Nitrogen mustard, cisplatin, cyclophosphaide
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
Toxicities include myelosuppression, anorexia, nausea
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
a. Phase spacific cytotoxic drugs
Toxicities include myelosupression kidney toxicity, nause anorexia, neurotoxicity
a. Phase spacific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
b. Phase non-specific cytotoxic drugs
