von willebrand disease Flashcards
germline mutations
Von willebrand Disease (VWD)
decreased platelet adhesion
Von willebrand Disease (VWD)
most prevalent congenital bleeding disorder
Von willebrand Disease (VWD)
affects both sexes due to its autosomal dominant inheritance pattern
Von willebrand Disease (VWD)
Severe bleeding - joint or organ
damage and even life-threatening situations.
Von willebrand Disease (VWD)
Symptoms include epistaxis, ecchymosis, menorrhagia, gastrointestinal tract bleeding, hematemesis, and surgical bleeding
Von willebrand Disease (VWD
leads to factor VIII deficiency
Von willebrand Disease (VWD)
When factor VIII levels decrease below 30% of normal, anatomic soft tissue bleeding
occurs
Von willebrand Disease (VWD)
most common bleeding disorder
Von willebrand Disease (VWD)
occurs equally among men and women, but
women are more likely to notice symptoms due to
heavy bleeding during menstrual periods and after
childbirth.
Von willebrand Disease (VWD)
caused by specific genetic mutations
Type 1 von Willebrand Disease
mild to moderate bleeding - dental extraction or surgery.
Type 1 von Willebrand Disease
excessive menstrual bleeding in women
Menorrhagia
