glanzmann thrombasthenia

Question 1

vitro clot retraction and a normal
platelet count

Answer 1

Glanzmann thrombasthenia

Question 2

consanguinity

Answer 2

Glanzmann thrombasthenia

Question 3

infancy, bleeding after circumcision and frequently with epistaxis and
gingival bleeding

Answer 3

Glanzmann thrombasthenia

Question 4

platelet membrane

Answer 4

Glanzmann thrombasthenia

Question 5

are less affected by abnormal clot retraction and fibrinogen binding

Answer 5

type 2 Glanzmann thrombasthenia disease

Question 6

thrombocytopenia and large platelets may be
seen with some of the mutations in these genes

Answer 6

Glanzmann
thrombasthenia

Question 7

Gene defects

Answer 7

Glanzmann
thrombasthenia

Question 8

monoclonal antibodies and flow cytometry

Answer 8

Glanzmann
thrombasthenia
(laboratory test)

Question 9

Normal platelet count, normal platelet morphology, and
a lack of platelet aggregation in response to all platelet
activating agents (including adenosine diphosphate
[ADP], collagen, thrombin, and epinephrine).

Answer 9

Glanzmann
thrombasthenia
(laboratory Features)

Question 10

Normal number of platelets but have a prolonged
bleeding time, which means it takes longer than usual
for a standardized cut to stop bleeding.

Answer 10

Glanzmann
thrombasthenia
(laboratory Features)

Question 11

Platelet aggregation studies are abnormal and show
that platelets are not able to clump together when
stimulated as they should to form platelet aggregates.

Answer 11

Glanzmann
thrombasthenia
(laboratory Features)

Question 12

Ristocetin

Answer 12

Glanzmann
thrombasthenia
(laboratory Features)

Question 13

transfusion of normal platelets

Answer 13

Glanzmann
thrombasthenia
(Treatment)