DISSEMINATED INTRAVASCULAR COAGULATION (DIC)

Question 1

This is a body-wide response to infection that causes inflammation. Sepsis is
the most common risk factor for DIC

Answer 1

sepsis

Question 2

This may be caused by cirrhosis of the liver, pancreatitis, severe injury,
burns, or major surgery

Answer 2

Major damage to organs or tissues

Question 3

Your body may overreact because of a failed blood transfusion, rejection of
an organ transplant, or a toxin such as snake venom.

Answer 3

Severe immune reactions

Question 4

These include the placenta separating from the uterus before delivery,
amniotic fluid entering the bloodstream, or serious bleeding during or after
delivery.

Answer 4

Serious pregnancy-related problems

Question 5

1. Bleeding from multiple sites (e.g., mucosal surfaces,
   venipuncture sites)
2. Petechiae and purpura
3. Ecchymoses
4. Hematuria
5. Altered mental status or coma (in severe cases)
6. Signs of organ dysfunction (e.g., renal failure, respiratory
   distress, hepatic failure)

Answer 5

DISSEMINATED
INTRAVASCULAR
COAGULATION
(DIC)

Question 6

1. Prolonged prothrombin time (PT) and activated partial
   thromboplastin time (aPTT)
2. Thrombocytopenia
3. Decreased fibrinogen levels
4. Elevated D-dimer levels
5. Evidence of hemolysis (e.g., increased lactate dehydrogenase,
   decreased haptoglobin)

Answer 6

DISSEMINATED
INTRAVASCULAR
COAGULATION
(DIC)

Question 7

1. Correction of underlying conditions (e.g., antibiotics for sepsis,
   delivery of the fetus in cases of obstetric complications)
2. Replacement of clotting factors and platelets with fresh frozen
   plasma and platelet transfusions
3. Administration of anticoagulant therapy in selected cases
4. Supportive care to manage organ dysfunction and maintain
   hemodynamic stability

Answer 7

DISSEMINATED
INTRAVASCULAR
COAGULATION
(DIC)