Vitamins part 3 tests and key words Flashcards
serum retinol
vitamin a
serum 25 (OH)
vitamin d
erythrocyte transketolase activity
thiamine b1
erythrocyte glutathione reductase activity (ERGAC)
increased in riboflavin B2 deficiency
ratio of urinary excretion of N1- methylnicotinamide & 2-pyridone less than 1
niacin B3
RBC folate
tissue stores/ chronic status
serum folate
recent intake
urine or blood methylmelonic acid
increased with vitamin b12 deficiency
cbc with increased MCV
non specific for vitamin b12 deficiency
increased plasma homocysteine
folate
cobalamin b12
pyridoxine b6
macrocytic anemia w/ hypersegmented neutrophils
folate
cobalamin v12
pyridoxal phosphate
pyridoxine b6
leukocyte or plasma ascorbic acid level
vitamin c
painful joints
vitamin c
water soluble vitamin involved with 1-C transfers?
folate
cobalamin b12
vitamin involved in catecholamine synthesis
vitamin c
vitamin involved with aa metabolism and interconversions
pyridoxine b6
reduction of Fe3+ –> Fe2+
vitamin C
metabolism of odd chain fatty acids
cobalamin b12
conversion of homocysteine –> methionine
folate
substituent of electron carrying substances NAD & NADP
niacin B3
part of 2 coenzymes FAD & FMN
riboflavin B2
metabolism of vitamin k, folate, b6, niacin b3
riboflavin b2
may bind at NA channel in nerve membranes to alter nerve conduction
thiamine b1
Beriberi: dry/ wet
wernicke-korsakoff:
thiamine b1 deficiency
triad in wernicke korsakoff?
ocular signs
ataxia
amnesia/ mental confusion
cheilosis, stomatitis, increased vascularization of conjunctiva, scrotal dermatitis
riboflavin b2
pellagra: 4Ds
Dermatitis, dementia, diarrhea, death
niacin b3 deficiency
lowers serum LDL
niacin b3
peripheral vasodilation/ flushing
niacin b3
alcoholics, refeeding, bariatric
thiamine b1
petechiae, bleeding gums, anemia, bruising
vitamin c deficiency
night blindness, xerophthalamia
vitamin a
supplementing in children with measels
vitamin a
- bone pain/ periosteal proliferation
- bone mineral loss
vitamin a toxicity
rickets rachitic rosary on ribs bowed legs widened metaphases painful bones fractures
vitamin d
bone pain
vitamin a overdose
vitamin d deficiency
decreased Ca and P
Increased alk phos
vitamin d
what is activated in the liver?
calcitriol = active form vitamin d
hypercalcemia vomiting seizures nephrocalcinosis soft tissue calcification
vitamin d toxicity
neurologic degradation
prematurity, fat malabsorption, short gut, CF
vitamin E
chronic gramulatous diseases
hypervitaminosis vitamin d
coag proteins
vitamin k
hemorrhagic disease of newborn
vitamin k
synthesized by intestinal bacteria
vitamin k
only from animal products
cobalamin b12,
social factors that increase risk of water soluble vitamin deficiency
poverty, chronic disease states, advanced age, dietary restrictions, high requirements