Vitamins part 1: summary & fat soluble Flashcards

1
Q

function of vitamin a

A
  • photochemical vision

- conjunctival membrane/ cornea

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2
Q

vitamin a deficiency

A
  • night blindness
  • xerophthalmia
  • immune deficiency: supplementation decreases child mortality 23-34%
  • infants/ child with measles: reduced mortality/ morbidity
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3
Q

vitamin a toxicity

A

Bone:

  • pain: periosteal prolif
  • mineral loss

-vomiting, increased ICP, headache, liver damage, birth defects

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4
Q

sources of vitamin a

A

preformed:
-liver, dairy, eggs, fish oil

Precursor: Carotenoids
-deep yellow, orange, green vegetables

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5
Q

vitamin a test

A

serum retinol

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6
Q

vitamin D function

A
  • hormone that maintains intracellular and extracellular Ca levels
  • intestinal absorption Ca and P
  • Innate immunity
  • Cell growth/ differentiation
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7
Q

Vitamin D deficiency

A
  • Rickets: inadequate maturation of cartilage and calcification
  • rachitic rosary on ribs
  • bowed legs
  • widened metaphyses
  • painful bones/ fractures
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8
Q

vitamin D toxicity

A

> 10,000 X for weeks

  • hypercalcemia
  • vomiting, seizures
  • nephrocalcinosis, soft tissue calcifinication
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9
Q

Vitamin D source

A

Preformed:

  • eggs, fish oil, fortified milk/ formula
  • D2 from plants

Precursor:
-in skin: converted to vit D3 by UV light

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10
Q

types of vitamin D

A

D3 activity&raquo_space; preformed D2

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11
Q

absorption of vitamin D

A
Chylomicrons:  
vitamin D2 or D3
-->
Liver:
25-hydroxy-cholecalciferol
-->
Kidney:
calcitrol (active)
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12
Q

vitamin D blood test

A

serum 25(OH)

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13
Q

classic triad late vitamin D deficiency

A

decreased serum Ca and P

Increased alk phos

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14
Q

vitamin E functions

A
  • antioxidant
  • free radical scavenger
  • cell membrane stabalizer
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15
Q

vitamin e source

A

polyunsaturated veg. oils

wheat germ

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16
Q

vitamin e deficiency

A

neurologic degeneration
loss of DTRs
Hemolytic Anemia

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17
Q

vitamin e toxicity

A

low toxicity

coagulopathy because very high doses inhibit vitamin k dependent factors

18
Q

vitamin e recommendations

A

supplement 400 IU D3 to all breastfed infants until 500ml/day infant formula or milk

19
Q

vitamin k function

A
  • essential for coagulation proteins

- factors: II, VII, IX, X

20
Q

vitamin K source

A

leafy veg.
fruits
seeds
synthesized by gut bacteria

21
Q

vitamin k deficiency

A
  • hemorrhagic disease of newborn
  • increased coag time
  • bleeding into skin, GI tract, CNS
22
Q

vitamin K recommendations

A

all newborns receive single iM dose 0.5-1 mg

23
Q

breastfed infants are at risk of what fat soluble vitamin deficiencies?

A

vitamin D

vitamin K

24
Q

people who use chronic antibiotics are at risk of what fat soluble vitamin deficiency?

25
people with chronic granulomatous diseases are at risk of what?
vitamin D hypervitaminosis
26
summary findings thiamin deficiency
neuro symptoms | Other: CHF (wet)
27
summary findings riboflavin deficiency
mouth lesions | other: conjunctiva
28
summary findings niacin
rash/skin findings neuro symptoms Other: diarrhea
29
summary findings folate deficiency
mouth lesions | anemia
30
summary findings b12
mouth lesions neuro symptoms anemia
31
summary findings b6
mouth lesions neuro symptoms anemia
32
summary findings vitamin c
``` rash/ skin findings mouth lesions neuro symptoms anemia other: joint pain ```
33
summary findings vitamin a
rash/ skin findings | other: eye/ blindness
34
summary findings vitamin d
other: rickets
35
summary findings vitamin e
neuro symptoms | anemia
36
summary findings vitamin K
rash/ skin findings | anemia
37
4 fat soluble vitamins
A D E K
38
water soluble vitamins: | non B complex
ascorbic acid/ vitamin C
39
water soluble vitamins: B complex Energy metabolism
thiamin b1 niacin b3 riboflavin b2
40
water soluble vitamins b complex hematopoietic
folic acid | cobalamin b12
41
water soluble vitamins b complex other
Pyridoxine b6