Vitamins As Coenzymes Flashcards

1
Q

What is the name of Vitamin B1? What is the active form? What does it contain?

A

Thiamine, Thiamine Pyrophosphate (TPP), Sulfur

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2
Q

What is the name of Vitamin B2? What is the active form?

A

Riboflavin, FAD FADH2 FMN

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3
Q

What is the name of Vitamin B2, What is the active form?

A

Riboflavin, FAD FADH2 FMN, fat metabolism

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4
Q

What is the name of Vitamin B5? What is the active form?

A

Pantothenic acid, CoASH (Coenzyme A)

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5
Q

What is the name of Vitamin B6? What is the active form? What is a deficiency in this Vitamin caused by?

A

Pyridoxine, Pyridoxal 5 phosphate, BC pills (also Mg)

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6
Q

What is the name of Vitamin B9? What is the active form?

A

Folic Acid, Tetrahydrofolate (THF) (H4Folate)

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7
Q

What is the name of Vitamin B12? What is the active form?

A

Cobalamin, Methyl cobalamin

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8
Q

What is the name of Vitamin B7? What is the active form? What is it made by? How does it become unavailable?

A

Biotin, Carboxybiotin, Good bacteria in colon; Raw eggs contain protein Avidin which binds biotin = unavail

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9
Q

What is the name of Vitamin C? What is the active form? How do you keep it in this active form? What can’t make VitC from sugar?

A

Ascorbic acid, Reduced state, with bioflavonoids (e.g. Quercitin, Rutin, Rose Hips), Guinea Pigs + Primates

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10
Q

What are the active forms of many Vitamins chemically composed of?

A

Vitamin + all/portion of ATP

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11
Q

Which vitamins (as a coenzyme) are involved in the Kreb’s cycle?

A

B1,2,3,5 (Thiamine, Riboflavin, Niacin, Pantothenic acid)

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12
Q

What vitamins (as coenzymes) take part in the methylation cycle?

A

B6,9,12 (Pyridoxine, Folic Acid, Cobalamin)

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13
Q

Homocysteine + Methyl B12 —>

A

Methionine + B12

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14
Q

Folic Acid + 2 (NADPH + H+) —>

A

Tetrahydrofolate (THF)

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15
Q

Methyl THF + B12 —>

A

THF + Methyl B12

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16
Q

THF + PLP (B6) —>

A

N5N10 Methylene THF

17
Q

dUMP + N5N10 Methylene THF —>

A

dTMP + THF

18
Q

What is in the ring of Purines (Adenine & Guanine)?

A

N10Formyl THF

19
Q

Define anemia

A

Decreased # RBCs

20
Q

What occurs in the absence of Folic acid & Vit B12? What should be done with these vitamins?

A

Cells too large but not enough of them (lack of mitosis) = Macrocytic anemia. Always give Vit B12 w/ Folic Acid