Protein Structure Flashcards
Define primary structure
Number and sequence of AAs
What are the bonds of the primary structure
Peptide bonds (covalent bonds)
Name the types of secondary structures
Alpha Helix, Beta pleated sheets, loop regions
What are the bonds of an ALPHA HELIX
H bonds, Van der Waals forces
What are the bonds of BETA PLEATED SHEETS
H bonds
Define tertiary structure
Folding for function
What are the bonds of TERTIARY STRUCTURE
Disulfide, H bonds, Salt bridges, Hydrophobic interactions
What types of proteins have tertiary structure
Enzymes, Hemaglobin
Define Quaternary structure
> 1 chain
What AAs are in the loop regions
Gly, Pro
Define a DIMERIC PROTEIN and name one
2 chains, Cu-Zn (superoxide dismutase)
Define TRIMERIC PROTEIN and name one
3 chains, Collagen (tropocollagen)
What AAs are in Collagen
Gly, Hydroxylysine, Hydroxyproline
What vitamin is needed to synthesize the AAs in trimeric proteins
Vitamin C
Define a TETRAMERIC PROTEIN and name one
4 chains, Hemoglobin
