Vitamin D Synthesis Flashcards
1
Q
Starting substance of vitamin d synthesis?
A
Cholesterol
2
Q
What is cholesterol converted to?
A
7 dehydrocholesterol
3
Q
What happens if 7 dehydrocholesterol is exposed to UV light?
A
It is converted to vitamin D3/cholecalciferol
4
Q
What happens to vitamin D3 in the liver?
A
It is converted to 25 (OH) cholecalciferol/vitamin D3 (calcitrol)
5
Q
What enzyme is required for vitamin D3 to be converted to 25 (OH) cholecalciferol in liver?
A
25 alpha hydroxylase
6
Q
What enzyme is turned on in the kidney in response to parathyroid hormone?
A
1 alpha hydroxylase
7
Q
What does 1 alpha hydroxylase do?
A
Converts 25 (OH) cholecalciferol to 1,25 (OH)2 cholecalciferol
