Hypothalamus-Adrenal Axis (HPA) Flashcards
Functions of aldosterone.
Acts on DCT.
principal cells.
Increases sodium potassium ATPase pump.
Increases sodium in blood.
decreases potassium in blood.
Increases potassium in urine.
Decreases sodium in urine.
What exists in zona glomerulosa?
Mineralcorticoids such as aldosterone.
What exists in zona fasciulata?
Glucocorticoids such as cortisol.
What exists in zona reticularis?
Androgens such as DHEA and androstenedione.
Function of cortisol
1.) liver elevates blood glucose
2.) Glut4 transporters blocked in muscle
3.) WBCs decreased and inflammation decreases
4.) immune defense decreased
Low sodium or high potassium in blood causes what?
Release of renin from JG cells.
What converts angiotensinogen to angiotension I ?
Renin
What converts angiotension I to angiotension II?
ACE
What causes release of aldosterone?
Angiotensin II
How else can aldosterone be released besides due to chronic stress?
By RAAS system