Hypothalamus-Adrenal Axis (HPA) Flashcards

1
Q

Functions of aldosterone.

A

Acts on DCT.
principal cells.
Increases sodium potassium ATPase pump.
Increases sodium in blood.
decreases potassium in blood.
Increases potassium in urine.
Decreases sodium in urine.

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2
Q

What exists in zona glomerulosa?

A

Mineralcorticoids such as aldosterone.

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3
Q

What exists in zona fasciulata?

A

Glucocorticoids such as cortisol.

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4
Q

What exists in zona reticularis?

A

Androgens such as DHEA and androstenedione.

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5
Q

Function of cortisol

A

1.) liver elevates blood glucose
2.) Glut4 transporters blocked in muscle
3.) WBCs decreased and inflammation decreases
4.) immune defense decreased

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6
Q

Low sodium or high potassium in blood causes what?

A

Release of renin from JG cells.

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7
Q

What converts angiotensinogen to angiotension I ?

A

Renin

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8
Q

What converts angiotension I to angiotension II?

A

ACE

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9
Q

What causes release of aldosterone?

A

Angiotensin II

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10
Q

How else can aldosterone be released besides due to chronic stress?

A

By RAAS system

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