Visual Physiology Dr. Pierce Flashcards
How are the three main cells connected in vision
Photoreceptors connect to bipolar cells which connect to ganglion cells which connect to the brain
What photoreceptor has many cells and many bipolar cells connected to one ganglion cell? What is the benefit?
Rods Sacrifice acuity to gain sensitivity allowing rods to operate in dim light
What photoreceptor has less convergence and sends info to only one bipolar cells that goes to only one ganglion cell? What’s the benefit?
Cones Maximizes acuity
Where do the density of rods and cones peak?
Rod density is greatest about 20 degrees from fovea and cones peak at the fovea
Explain what happens to photoreceptors in the dark.
- Photoreceptors Depolarize in the Dark creating a graded potential
- Glu is released
- Binds MgluR6 acting inhibitory on bipolar cells
- Bipolar cell does not depolarize so no impulse is sent to the brain
(Glutamate release from rods/cones is highest in dark and not stimuluated by photons)
What happens to photoreceptors in the light?
- They hyperpolarize and do not create graded potentials
- No glutamate is released
- Bipolar cells spontaneously depolarizes releasing Glu on Ganglion cells
- Ganglion cell generates an AP
- Send signal to brain
(Glutamate release from rods/cones is low in light )
What are the direct targets of the retina? Describe 3 of them
- LGN:
- Major target, regulates flow of info to primary VC
- Superior colliculus:
- Connects tectospinal tract sends info to ant. horn cells
- makes map of visual space to make correct motor responses to move eyes
- Pretectum:
- Pupillary light reflex- sends projections to edinger westphal then ciliary ganglion
What are two more of the direct targets of the retina? (Continuation of another card)
- Hypothalamus:
- visual imput to drive light dark circadian rhythm and endocrine fxns
- Accessory optic nuclei:
- Adv. visual processing
- optokinetic nystagmus in response to prolonged large field motion
What is the fxn of LGN
- Control motion of eyes and converge on point of interest
- Control focus of eyes based on distance
- Determine relative postiion of objects to map them
- Detet movement relative to object
V1 function
Edges and contours of objects
V2 function
Depth perception
V3a fxn
Identify if motion is occuring, yes or no
V4 fxn
Complete processing of color inputs
- lesions can cause achromatopsia
MT/V5 fxn
Tracks motion across a scene with directionality by responding to moving edges
What are occular dominance columns? What are Orientation columns? What are blobs?
- Columns in the visual cortex that respond to one eye or the other. They span all six layers. Truly look like stripes. Prominent in V1.
- Respond to different orientations, each column responds to visual line stimuli of different angles. Spans all 6 layers. Truly look like swirls
- Neurons that are sensitive to color and assemble into cylindrical shapes. All layers. Polka dots, cytochrome oxidase stain shows