Virus pathologies Flashcards

1
Q

Colorado tick fever: saddleback fever pattern; travel to mountain West

A

Colorado tick fever virus

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2
Q

CMV infectious mononucleosis: heterophile Ab negative; Owl’s eyes cells
Congenital systemic CMV: deafness

A

Cytomegalovirus (CMV; HHV-5)

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3
Q
exanthem subitum (aka roseola):  rash that develops after a fever resolves
heterophile Ab negative mononuceosis
A

HHV-6 & HHV-7

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4
Q

EBV infectious mononucleosis: Heterophile Ab positive mono
Burkitt lymphoma: t(8:14)
Hodgkin & non-Hodgkin lymphoma
nasopharyngeal lymphoma
X-linked lymphoproliferative disease: inherited mutation in SAP adapeter

A

Epstein Barr virus (EBV; HHV-4)

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5
Q

in immunocompromised patients only: Kaposi sarcoma, primary effusion lymphoma, multifocal Castlemans disease

A

Kaposi sarcoma herpes virus (KSHV; HHV-8)

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6
Q

erythema infectiosum: fiery red rash on cheek. Transient aplastic crisis: in patients with underlying anemia

A

parvovirus B19

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7
Q

Acute T cell lymphoma / leukemia (ATL): Viral transcription factor Tax drives proliferation; blocks apoptosis.
HAM/TSP: Inflammation on the spine

A

Human T lymphotrophi virus -1 (HTLV-1; related: HTLV-2)

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8
Q

Acquired immunodeficiency syndrome: depletion of CD4 T cells allows opportunistic infections

A

Human immunodeficiency virus -1 (HIV-1; related: HIV-2)

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9
Q

Hemorrhagic fever

A

Ebola virus (EBOV)

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