Mediators Flashcards
1
Q
Histamine
A
redness, heat, swelling, airway constriction, vasodilation, ithcing, pain, wheal & flare - NOT chemotaxis
2
Q
PGE2
A
vasodilate, increase vascular permeability, cause pain
3
Q
PGD2
A
bronchoconstriction
4
Q
TXA2 (thromboxane)
A
platelet aggregation (vasconstriction)
5
Q
PGI2
A
opposes platelet aggregation (vasodilation) - pain
6
Q
LTB4
A
chemotaxis of white cells and reduces pain
7
Q
LTC4, LTD4, LTE2
A
airway constriction, eosinophil chemotaxis, vascular permeabilty, dc maturation, mucous production.
8
Q
Kinins (Bradykinin)
A
potent vasodilator. Edema formation. Pain. Gut contracts. Smooth muscle airway contracts. Catecholamine release. Prostaglandin release. Vascular pemerability.
