Leukemia and Lymphoma Genetics and Translocations Flashcards by Babe Lincoln | Brainscape

Q

t(15:17)

A

AML M3, good

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Q

Inv(16)

A

AML M4, good

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Q

t(8:21)

A

AML M2, good

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Q

11q23

A

AML, bad

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Q

FLT-3

A

AML, bad

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Q

del 5,7, trisomy 8

A

AML, bad

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Q

t(11;17)

A

AML M3, bad

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Q

13q-,trisomy 12, 11q-,17p-

A

CLL, bad-worse

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Q

CD38-

A

CLL, good = mutated IgVh

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Q

ZAP-70+

A

CLL, bad (correlates with CD38+)(and IgVh)

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Q

t(9:22)(q34, q11)

A

BCR-ABL1, bad

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Q

t(11:14)

A

Mantle cell lymphoma (over-expression Cyclin D1)

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Q

t(14:18)

A

Follicular Lymphoma IgH + Bcl-2

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Q

t(8:14)

A

Burketts Lymphoma, c-myc + IgH

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