Oncology Drugs

Question 1

First / Non-classical Alkylator, platinum complex/ Inorganic complex/ Germ cell tumors, bladder cancer

Answer 1

Cisplatin

Question 2

First / Non-classical Alkylator, platinum complex / Inorganic complex / Epithelial malignancies, second-line treatment
of lymphomas

Answer 2

Carboplatin

Question 3

First / Alkylator, nitrogen mustard / small molecule / Breast cancer, lymphomas,
immunosuppression, stem cell mobilization

Answer 3

Cyclophosphamide

Question 4

First / Topoisomerase inhibitor / small molecule / Breast cancer, lymphomas

Answer 4

Doxorubicin

Question 5

First / Antimetabolite, pyrimidine analog / small molecule / GI cancers

Answer 5

5-Fluorouracil

Question 6

First / Signal Transduction inhibitor, TKI / small molecule / B-cell malignancies, especially CLL

Answer 6

Ibrutinib

Question 7

First / Signal Transduction inhibitor, TKI / small molecule / CML, GIST, Ph+ ALL

Answer 7

Imatinib

Question 8

First / Signal Transduction inhibitor, Receptor super-agonist / Peptide / Prostate and Breast cancers

Answer 8

Leuprolide

Question 9

First / Immune checkpoint inhibitor, blocking antibody / Monoclonal Antibody / Melanoma, Lung cancer, Renal Cell
Carcinoma

Answer 9

Nivolumab

Question 10

First / Anti-tubulin / small molecule / Epithelial malignancies, especially Breast and
Ovarian

Answer 10

Paclitaxel

Question 11

First / Immune therapy, antibody painting / Monoclonal Antibody / CD20 expressing B-cell malignancies

Answer 11

Rituximab

Question 12

First / Signal Transduction inhibitor, Receptor antagonist / small molecule / Breast cancer

Answer 12

Tamoxifen

Question 13

First /Signal Transduction inhibitor, Receptorm antagonist / Monoclonal Antibody / Her-2 over-expressing Breast and upper GI
cancers

Answer 13

Trastuzumab

Question 14

Second / Signal Transduction inhibitor, ligand

reduction / small molecule / Breast cancer

Answer 14

Anastrozole

Question 15

Second / Alkylator, nitrogen mustard / small molecule / Lymphomas

Answer 15

Bendamustine

Question 16

Second / Proteasome inhibitor / small molecule / Multiple myeloma, mantle cell lympoma,
Waldenstrom’s

Answer 16

Bortezomib

Question 17

Second / Signal Transduction inhibitor, TKI / small molecule / Lung cancers with ALK or ROS1 activation, cmet
overexpressing thyroid cancer

Answer 17

Crizotinib

Question 18

Second / Antimetabolite, purine analog / small molecule / AML, second-line lymphoma

Answer 18

Cytarabine arabinoside

Question 19

Second / Signal Transduction inhibitor, Receptor

antagonist / small molecule / Prostate

Answer 19

Enzalutamide

Question 20

Second / Topoisomerase inhibitor / small molecule / Germ cell tumors, Lymphoma

Answer 20

Etoposide

Question 21

Second / Antimetabolite, pyrimidine analog / small molecule / Pancreas cancer, Bladder cancer, widely used
in second-line setting

Answer 21

Gemcitabine

Question 22

Second / Antimetabolite / small molecule / Many cancers

Answer 22

Methotrexate

Question 23

Second Signal Transduction inhibitor, Receptor

antagonist / Monoclonal Antibody / EGFR driven cancers of aerodigestive tract

Answer 23

Panitumumab

Question 24

Second / Signal Transduction inhibitor, TKI / small molecule / Renal cell carcinoma

Answer 24

Pazopanib

Question 25

Second / Non-classical Alkylator / small molecule / Brain cancer

Answer 25

Temazolamide