T Cell Receptors and the MHC Complex Flashcards
Th1 CD4+ T Cells polarized by:
IL-12, IL-18, and INF gamma
Th1 CD4+ T Cells Effector Cytokines Produced
IFN gamma, and TNF
Th1 CD4+ T Cell Master Transcriptional Regulator
T-bet
Th17 CD4+ T Cells polarized by:
TGF-beta, IL-1, IL-6, and IL-23
Th17 CD4+ T Cells Effector Cytokines Produced
IL-17 and IL-22
Th17 CD4+ T Cell Master Transcriptional Regulator
RORyt
Th2 CD4+ T Cells Polarized by:
IL-4
Th2 CD4+ T Cells Effector Cytokines Produced
IL-4, IL-5, and IL-13
Th2 CD4+ T Cell Master Transcriptional Regulator
GATA3
Follicular Helper CD4+ T Cells, Tfh, Polarized by
IL-6 and IL-21
Follicular Helper CD4+ T Cells, Tfh, Effector Cytokines Produced:
IL-4 and IL-21
Follicular Helper CD4+ T Cells (Tfh), Master Transcriptional Regulator
Bcl-6
Regulatory CD4+ T Cells (Treg), Polarized by:
IL-2 and TGF-beta
Regulatory CD4+ T Cells (Treg), Effector cytokines produced:
IL-10 and TGF-Beta
Regulatory CD4+ T Cells (Treg),
FOXP3