T Cell Receptors and the MHC Complex Flashcards

1
Q

Th1 CD4+ T Cells polarized by:

A

IL-12, IL-18, and INF gamma

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2
Q

Th1 CD4+ T Cells Effector Cytokines Produced

A

IFN gamma, and TNF

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3
Q

Th1 CD4+ T Cell Master Transcriptional Regulator

A

T-bet

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4
Q

Th17 CD4+ T Cells polarized by:

A

TGF-beta, IL-1, IL-6, and IL-23

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5
Q

Th17 CD4+ T Cells Effector Cytokines Produced

A

IL-17 and IL-22

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6
Q

Th17 CD4+ T Cell Master Transcriptional Regulator

A

RORyt

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7
Q

Th2 CD4+ T Cells Polarized by:

A

IL-4

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8
Q

Th2 CD4+ T Cells Effector Cytokines Produced

A

IL-4, IL-5, and IL-13

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9
Q

Th2 CD4+ T Cell Master Transcriptional Regulator

A

GATA3

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10
Q

Follicular Helper CD4+ T Cells, Tfh, Polarized by

A

IL-6 and IL-21

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11
Q

Follicular Helper CD4+ T Cells, Tfh, Effector Cytokines Produced:

A

IL-4 and IL-21

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12
Q

Follicular Helper CD4+ T Cells (Tfh), Master Transcriptional Regulator

A

Bcl-6

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13
Q

Regulatory CD4+ T Cells (Treg), Polarized by:

A

IL-2 and TGF-beta

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14
Q

Regulatory CD4+ T Cells (Treg), Effector cytokines produced:

A

IL-10 and TGF-Beta

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15
Q

Regulatory CD4+ T Cells (Treg),

A

FOXP3

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