virulence factors Flashcards
1
Q
staph aureus
A
- proteins that disable our immune sys (protien A)
- tissue tunnelling proteins
- exotoxin assault proteins
2
Q
staph epidermidis
A
biofilms
3
Q
grp A beta hemolytic strep (strep pyrogens)
A
- M protein
- streptolysin O enz
- streptolysin S enz
4
Q
strep pnemoniae
A
polysaccharide capsule: prevent phago
5
Q
bacillus anthracis
A
unique protein capsule from pOX2, which releases exotoxins:
- edema factor - increases cAMP
- protective ag - promote EF into mfs
- lethal factor - TNF death
6
Q
bacillus cereus
A
enterotoxins:
- heat labile toxin
- heat stable toxin
7
Q
clostridium tetani
A
tatanospasmin –>tetany of m’s
8
Q
clostridium botulinum
A
neurotoxin that blocks Ach release –> flaccid paralysis
9
Q
clostridium difficile
A
exotoxin A: diarrhea
exotoxin B: cytotoxic to colonic cells
10
Q
clostridium perfringens
A
exotoxins that affect tissue, m, gut
11
Q
cornybacterium diptheriae
A
exotoxins that target the <3 and brain
12
Q
listeria monocytogenes
A
listeriolysin O: avoid phagolysosomes
13
Q
neisseria meningitides
A
- capsule
- endotoxin
- IgA1 protease
- steal Fe from humans
- pilli
14
Q
neisseria gonorrhoeae
A
- pilli
- outer mem proteins
- opa proteins
15
Q
e coli
A
- mucosal interaction: able to invade
- exotoxins:heat labile and heat stable and shiga-like toxin
- LPS endotoxin
- takes Fe from human transferrin or lactoferrin
