Virulence Factor

Question 1

Colonizes anterior mares, nasopharynx, perianal area, skin, mucosa

Answer 1

Staph aureus

Question 2

Skin flora, assoc with bacterial endocarditis ff prosthetic heart valve, blood culture contaminant, hospital acquired UTI

Answer 2

Staph epidermidis

Question 3

Flora of skin, genito urinary tract and mucosa. Most common uti in sexually active fem

Answer 3

Staph saprophyticus

Question 4

Virulence factor causes scalded skin syndrome

Answer 4

Exfoliative toxin : serine protease

Question 5

Ritters disease 90% of body is affected or Perphigus neonatorum/bullos impetigo

Answer 5

Staph aureus: exfoliative toxin/ epidermolytic toxin

Question 6

Toxic to wbcs initiating deeper tissue infection

Answer 6

Gamma toxin: Panton Valentin Leukocidin

Question 7

Induces IL1 secretion causing fever, vomiting, rash and hypotension lead to shock and death

Answer 7

Staph aureus
Entero toxin F: Toxic shock syndrome toxin 1

Question 8

Virulence factor of Staph aureus digests connective tissue matrix

Answer 8

Hyaluronidase: Duran Reynal Factor/ Spreading factor

Question 9

Treatment for MRSA

Answer 9

Vancomycin

Question 10

Subsurface hemolysin oxygen labile. Toxic to RBCs, WBC, and platelets

Answer 10

Streptolysin O

Question 11

Induces antibody response Anti streptolysin O.stab inside the gel agar anaerobe

Answer 11

S.pyogenes: Strep O

Question 12

Surface antigen oxygen stable. Lysis WBCs and non immunogenic

Answer 12

Strep pyogenes: Streptolysin S

Question 13

Associated with SCARLET FEVER and Strep Toxic Like syndrome

Answer 13

Strep Exotoxin ABC SPE
Exotoxin A
Strep.pyogenes

Question 14

Post streptococcal sequelae. Common infections of Strep pyogenes

Answer 14

Rheumatic heart fever
Acute glomerulonephritis

Question 15

Cross reactive antibodies agains streptococcal antigens and human heart tissues alike. Causes fever and inflammation of heart and blood vessels

Answer 15

Rheumatic heart fever by strep pyogenes

Question 16

Protein that able to bind beta globulin factor H, cant degrade alternate pathway activation of immune system

Answer 16

M protein of Strep pyogenes

Question 17

Bacterial pharyngitis and tonsilitis

Answer 17

Strep pyogenes

Question 18

Neonatal meningitis

Answer 18

Strep agalactiae

Question 19

Causes pneumonia, obstetric complications during delivery. Endometritsmis and woubd infection

Answer 19

Strep agalactiae

Question 20

Resembles Strep pyogenes infections. Large Beta hemolytic colonies

Answer 20

Grp C: Strep dysgalactiae sub equisimilis

Question 21

Nosocomial infection UTI catherization, bacteremia (hemodialysis, surgery) endocarditis (prothetic heart valves)

Answer 21

Grp D enterococcos

Question 22

Causes subacute bacterial endocarditis from patient with damaged heart valves. Causes bacteremia, septicemia and cavities

Answer 22

Viridans Strep Grp ACFGN

Question 23

Assoc disease. Lobar and community acquired pneumonia
Causes sinusitis, otitis media, bacteremia

Answer 23

Strep pneumoniae

Question 24

Meningitis aged group affected by Strep pneumoniae

Answer 24

30 to 99
Late adult

Question 25

Neonates meningitis causative agents

Answer 25

1. Strep agalactiae
2. E.coli
3. L.monocytogenes

Question 26

1 to 5 years old meningitis

Answer 26

Haemophilus influenzae

Question 27

Adult to old aged or immunocompressed people meningitis CA

Answer 27

1. Strep pneumoniae
2. Staph aureus

Question 28

most common agents through nasopharyngeal swab

Answer 28

1. H.influenzae
2. N.meningitidis
3. B.pertussis
4. MRSA
5. Diphtheriae