CLinchem P2 Flashcards
In which of the following conditions would a normal level of creatine kinase be found?
Hepatitis
Which of the following enzymes of heme biosynthesis is inhibited by lead?
Delta-aminolevulinate dehydratase
Lead inhibits 3 enzymes in the heme biosynthesis pathway: delta-aminolevulinic acid dehydratase (ALAD), coproporphyrinogen oxidase, and ferrochelatase.
What substance gives feces its normal color?
Urobilin
In which of the following conditions does decreased activity of glucuronyl transferase result in increased unconjugated bilirubin and kernicterus in neonates?
Crigler-Najjar syndrome
On electrophoresis at alkaline pH, which of the following is the slowest migrating hemoglobin?
Hb C
A 9-month-old boy from Israel has gradually lost the ability to sit up, and develops seizures. He has an increased amount of a phospholipid called ganglioside in his neurons, and he lacks the enzyme hexosaminidase A in his leukocytes. These findings suggest:
Tay-Sachs disease
In spectrophotometric determination, which of the following is the formula for calculating the absorbance of a solution?
absorptivity x light path x concentration
An increase in serum acetone is indicative of a defect in the metabolism of:
Carbohydrates
Increase in ketones is found when there is a decreased use of carbohydrates, such as in diabetes.
A patient with hemolytic anemia will:
Show a decrease in glycated Hb value
The preparation of a patient for standard glucose tolerance testing should include:
A high carbohydrate diet for 3 days
Calibration is defined as:
Comparison of an instrument measure or reading to a known physical constant
Chain-of-custody procedures must be followed for:
Blood specimens for alcohol level determination
