Virology Flashcards
1
Q
What is the half life of CMV?
A
5-8 days
2
Q
In what patient should CMV blood PCR be trended? How often?
A
Transplant patients with CMV infection
Weekly
3
Q
How much should CMV go down for it to be an important decrease?
A
3 fold or 0.5 a log
4
Q
What resistance mutation in CMV confers ganciclovir resistance?
A
UL97
5
Q
What resistance mutation in CMV confers ganciclovir and cidofovir if selected for AND/OR foscarnet if selected for resistance?
A
UL54
–> Later mutation, UL97 is more common.
6
Q
Who should you consider testing for CMV viral resistance?
A
Those who have had 6 weeks of treatment for CMV including 2 weeks of full dose testing.
