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ID Review > Resistance Mutations > Flashcards

Resistance Mutations Flashcards

1
Q

Medications that do worse with M184V?

A

Lamivudine
Emtricitabine
Abacavir

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2
Q

Medications that do worse with K65R?

A

Tenofovir
Abacavir
Didanosine
Stavudine

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3
Q

Medications that do worse with T69 Insertion

A

Tenofovir
Abacavir
Didanosine
Thymadine Analogs
Lamivudine
Emtricitabine

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4
Q

Medications that do worse with Q151M

A

Abacavir
Didanosine
Thymidine analogs
Lamivudine
Emtricitabine

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5
Q

Medications that do worse with L74V

A

Didanosine
Abacavir

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6
Q

Medications that do worse with K103N

A

Efavirenz (Most important)
Nevirapine

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7
Q

Medications that do worse with Y181C

A

Nevirapine (most important)
Efavirenz
Rilpivirine
Etravirine

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8
Q

Medications that do worse with E138K or K101E

A

Rilpivirine

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9
Q

Medications that do worse with Q148R

A

Raltegravir
Elvitegravir
–> DTG needs BID dosing

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10
Q

Medications that do worse with N155H

A

Raltegravir
Elvitegravir

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11
Q

Medications that do worse with Q148 AND N155 together

A

All INSTIs

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12
Q

Medications that do worse with Y143C

A

RAL

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13
Q

Medications that do worse with R263K

A

DTG

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14
Q

Medications that do worse with I50L

A

Atazanavir

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15
Q

Medications that do better with M184V

A

Tenofovir
Zidovudine

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16
Q

Medications that do better with K65R

A

Zidovudine

17
Q

Medications that do better with L74V

A

Tenofovir
Zidovudine

18
Q

Medications that do better with K103N

A

Rilpivirine
Etravirine

19
Q

Medications that do better with I50L

A

All other PI

20
Q

Medications that do worse with A98G

A

nevirapine and efavirenz

21
Q

Medications that do better with A98G

A

etravirine

22
Q

Medications that due worse with E138K

A

rilpivirine AND etravirine

23
Q

What is the only NRTI that has activity with Q151M

A

tenofovir

ID Review (25 decks)

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