Virology Flashcards

1
Q

All viruses are haploid except

A

Retroviruses

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2
Q

All DNA viruses have double-stranded DNA except

A

Parvovirus

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3
Q

All RNA viruses have single-stranded RNA except

A

Reovirus

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4
Q

All double-stranded DNA viruses are icosahedral except

A

Pox virus

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5
Q

Circular DNA, enveloped, dsDNA

A

Hepadnaviridae

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6
Q

Linear DNA, enveloped, dsDNA

A

Herpes virus

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7
Q

Circular DNA, naked, dsDNA

A

Papovaviridae

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8
Q

Linear DNA, naked, dsDNA

A

Adenoviridae

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9
Q

Icosahedral, enveloped, +ssRNA

A

Flaviviridae
Retroviridae
Togaviridae

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10
Q

Helical, enveloped, +ssRNA

A

Coronavirus

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11
Q

Icosahedral, naked, +ssRNA

A

Astroviridae
Caliciviridae
Picornaviridae

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12
Q

Bullet shaped virus

A

Rhabdoviridae

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13
Q

Helical, enveloped, -ssRNA

A

Filoviridae
Orthomyxoviridae
Paramyxoviridae

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14
Q

Arenaviridae and Bunyaviridae are described as:

A

Helical, enveloped, ambisense and negative sense ssRNA

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15
Q

Causes of heterophil-negative mononucleosis

A

Cytomegalovirus

Toxoplasmosis

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16
Q

Three diseases that can present with blueberry muffin lesions

A

Cytomegalovirus
Congenital rubella
Neuroblastoma

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17
Q

Parvovirus B19 can cause aplastic crisis in patients with

A

Sickle cell disease

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18
Q

“Slapped cheeks” are seen in this disease caused by Parvovirus B19

A

Erythema infectiosum

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19
Q

Fetal infection with Parvovirus B19 can cause:

A

Hydrops fetalis

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20
Q

Adenovirus can have this genitourinary manifestation

A

Hemorrhagic cystitis

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21
Q

Most common cause of conjunctivitis

A

Adenovirus

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22
Q

Cells with marked formation of cytoplasmic vacuoles in HPV infection

A

Koilocytes

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23
Q

HPV strains that are common causes of skin and plantar warts

A

HPV 1 to 4

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24
Q

Most common viral sexually transmitted disease

A

Human papillomavirus (HPV 6 and 11)

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25
Also known as anogenital warts
Condyloma acuminata
26
HPV strains associated with carcinoma of the cervix, penis, and anus
HPV 16, 18, 31, and 33
27
Multinucleated giant cells on Tzanck smear are seen in infections caused by
Herpes simplex 1 and 2
28
Drug of choice in herpes simplex
Acyclovir
29
HSV infection in the finger commonly seen in healthcare workers
Herpetic whitlow
30
HSV-1 can cause encephalitis in this region of the brain
Temporal lobe
31
Genital and neonatal herpes are cause by this viral strain
HSV-2
32
Most common infectious cause of congenital anomalies
Cytomegalovirus
33
CMV retinitis presents in CD4 counts of
34
Drug of choice in cytomegalovirus infections
Gancyclovir
35
Also known as "kissing disease"
Infectious mononucleosis
36
Etiology of infectious mononucleosis
Epstein-Barr virus
37
Four malignancies associated with Epstein-Barr virus
B cell lymphoma Burkitt's lymphoma Hairy leukoplakia Nasopharyngeal carcinoma
38
The infective form of hepatitis B virus is also known as the:
Dane particle
39
Necrotic hepatocytes in hepatitis B virus
Councilman bodies
40
Autoimmune vasculitides in hepatitis B
Polyarteritis nodosa
41
Treatment for hepatitis B
Interferon | Lamivudine
42
Identify the time period: HBsAg (-), Anti-HBs (-), Anti-HBc (+) IgM, HBeAg (-)
Window period
43
Identify the time period: HBsAg (+), Anti-HBs (-), Anti-HBc (-), HBeAg (+)
Incubation period
44
Identify the time period: HBsAg (-), Anti-HBs (+), Anti-HBc (+) IgG, HBeAg (-)
Complete recovery
45
Cells affected in polio
Anterior horn cells
46
Cause of herpangina, hand-foot-and-mouth disease, and hemorrhagic conjunctivitis
Coxsackie virus type A
47
Most common viral cause of myocarditis and pericarditis
Coxsackie virus type B
48
Population group that are at high risk of mortality from hepatitis E virus
Pregnant women
49
Hepatitis viruses that are transmitted via the orofecal route
Hepatitis A and E
50
Most common cause of nonbacterial diarrhea in adults
Norwalk virus
51
Most common cause of childhood diarrhea
Rotavirus
52
Influenza strains that have humans as the only host
Influenza B
53
These influenza strains are capable of antigenic shifts
Influenza A
54
Drug of choice in influenza
Oseltamivir
55
Histopathologic finding in measles
Warthin-Finkeldey bodies
56
Bright red lesions with a white central dot on the buccal mucosa seen in measles
Koplik spots
57
Also known as Damson disease
Subacute sclerosing panencephalitis
58
Complications of measles are prevented by supplementation with
Viramin A
59
In mumps, there is increase in pain when drinking
Citrus drinks
60
Two important complication of mumps
Meningits | Orchitis
61
Most common cause of bronchiolitis
Respiratory syncytial virus
62
Ribavirin can be used in infections caused by
Hepatitis C | Respiratory syncytial virus
63
Cause of laryngotracheobronchitis
Parainfluenza virus
64
Treatment for croup
Supportive (racemic epinephrine)
65
Radiologic finding in croup
Steeple sign
66
Histopathologic finding in rabies
Negri bodies
67
Animal reservoir of SARS coronavirus
Horseshoe bat
68
SARS coronavirus binds to these receptors in the lungs
ACE-2
69
Breakbone fever is seen in
Dengue
70
Vector of dengue
Aedes aegypti
71
Most prevalent blood-borne pathogen
Hepatitis C
72
Most common indication for liver transplant is infection with
Hepatitis C
73
Treatment of hepatitis C infection
Interferon | Ribavirin
74
Common location of lymphadenopathy in rubella
Posterior auricular
75
Also known as three-day measles
Rubella / German measles
76
Most common cardiac anomaly in congenital rubella
Patent ductus arteriosus
77
HIV protein used for attachment to CD4
gp120
78
gp120 and gp41 are encoded in this gene
env
79
This HIV gene encodes the structural proteins for nucleocapsid and matrix
gag
80
Phase of HIV infection wherein there is rapid viral replication but HIV test is negative
Phase 1 - Window period
81
Mycobacterium avium infection, histoplasmosis, and CMV retinitis are seen at CD4 counts of less than
50
82
Pneumocystis jiroveci pneumonia is seen at CD4 counts of less than
200
83
The only DNA virus among the hepatitis viruses
Hepatitis B virus
84
What is the diagnostic test of choice for influenza?
Reverse PCR