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Microbiology and Parasitology > Virology > Flashcards

Virology Flashcards

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Biology 101 flashcards
1
Q

All viruses are haploid except

A

Retroviruses

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2
Q

All DNA viruses have double-stranded DNA except

A

Parvovirus

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3
Q

All RNA viruses have single-stranded RNA except

A

Reovirus

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4
Q

All double-stranded DNA viruses are icosahedral except

A

Pox virus

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5
Q

Circular DNA, enveloped, dsDNA

A

Hepadnaviridae

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6
Q

Linear DNA, enveloped, dsDNA

A

Herpes virus

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7
Q

Circular DNA, naked, dsDNA

A

Papovaviridae

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8
Q

Linear DNA, naked, dsDNA

A

Adenoviridae

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9
Q

Icosahedral, enveloped, +ssRNA

A

Flaviviridae
Retroviridae
Togaviridae

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10
Q

Helical, enveloped, +ssRNA

A

Coronavirus

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11
Q

Icosahedral, naked, +ssRNA

A

Astroviridae
Caliciviridae
Picornaviridae

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12
Q

Bullet shaped virus

A

Rhabdoviridae

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13
Q

Helical, enveloped, -ssRNA

A

Filoviridae
Orthomyxoviridae
Paramyxoviridae

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14
Q

Arenaviridae and Bunyaviridae are described as:

A

Helical, enveloped, ambisense and negative sense ssRNA

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15
Q

Causes of heterophil-negative mononucleosis

A

Cytomegalovirus

Toxoplasmosis

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16
Q

Three diseases that can present with blueberry muffin lesions

A

Cytomegalovirus
Congenital rubella
Neuroblastoma

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17
Q

Parvovirus B19 can cause aplastic crisis in patients with

A

Sickle cell disease

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18
Q

“Slapped cheeks” are seen in this disease caused by Parvovirus B19

A

Erythema infectiosum

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19
Q

Fetal infection with Parvovirus B19 can cause:

A

Hydrops fetalis

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20
Q

Adenovirus can have this genitourinary manifestation

A

Hemorrhagic cystitis

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21
Q

Most common cause of conjunctivitis

A

Adenovirus

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22
Q

Cells with marked formation of cytoplasmic vacuoles in HPV infection

A

Koilocytes

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23
Q

HPV strains that are common causes of skin and plantar warts

A

HPV 1 to 4

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24
Q

Most common viral sexually transmitted disease

A

Human papillomavirus (HPV 6 and 11)

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25
Q

Also known as anogenital warts

A

Condyloma acuminata

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26
Q

HPV strains associated with carcinoma of the cervix, penis, and anus

A

HPV 16, 18, 31, and 33

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27
Q

Multinucleated giant cells on Tzanck smear are seen in infections caused by

A

Herpes simplex 1 and 2

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28
Q

Drug of choice in herpes simplex

A

Acyclovir

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29
Q

HSV infection in the finger commonly seen in healthcare workers

A

Herpetic whitlow

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30
Q

HSV-1 can cause encephalitis in this region of the brain

A

Temporal lobe

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31
Q

Genital and neonatal herpes are cause by this viral strain

A

HSV-2

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32
Q

Most common infectious cause of congenital anomalies

A

Cytomegalovirus

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33
Q

CMV retinitis presents in CD4 counts of

A
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34
Q

Drug of choice in cytomegalovirus infections

A

Gancyclovir

35
Q

Also known as “kissing disease”

A

Infectious mononucleosis

36
Q

Etiology of infectious mononucleosis

A

Epstein-Barr virus

37
Q

Four malignancies associated with Epstein-Barr virus

A

B cell lymphoma
Burkitt’s lymphoma
Hairy leukoplakia
Nasopharyngeal carcinoma

38
Q

The infective form of hepatitis B virus is also known as the:

A

Dane particle

39
Q

Necrotic hepatocytes in hepatitis B virus

A

Councilman bodies

40
Q

Autoimmune vasculitides in hepatitis B

A

Polyarteritis nodosa

41
Q

Treatment for hepatitis B

A

Interferon

Lamivudine

42
Q

Identify the time period: HBsAg (-), Anti-HBs (-), Anti-HBc (+) IgM, HBeAg (-)

A

Window period

43
Q

Identify the time period: HBsAg (+), Anti-HBs (-), Anti-HBc (-), HBeAg (+)

A

Incubation period

44
Q

Identify the time period: HBsAg (-), Anti-HBs (+), Anti-HBc (+) IgG, HBeAg (-)

A

Complete recovery

45
Q

Cells affected in polio

A

Anterior horn cells

46
Q

Cause of herpangina, hand-foot-and-mouth disease, and hemorrhagic conjunctivitis

A

Coxsackie virus type A

47
Q

Most common viral cause of myocarditis and pericarditis

A

Coxsackie virus type B

48
Q

Population group that are at high risk of mortality from hepatitis E virus

A

Pregnant women

49
Q

Hepatitis viruses that are transmitted via the orofecal route

A

Hepatitis A and E

50
Q

Most common cause of nonbacterial diarrhea in adults

A

Norwalk virus

51
Q

Most common cause of childhood diarrhea

A

Rotavirus

52
Q

Influenza strains that have humans as the only host

A

Influenza B

53
Q

These influenza strains are capable of antigenic shifts

A

Influenza A

54
Q

Drug of choice in influenza

A

Oseltamivir

55
Q

Histopathologic finding in measles

A

Warthin-Finkeldey bodies

56
Q

Bright red lesions with a white central dot on the buccal mucosa seen in measles

A

Koplik spots

57
Q

Also known as Damson disease

A

Subacute sclerosing panencephalitis

58
Q

Complications of measles are prevented by supplementation with

A

Viramin A

59
Q

In mumps, there is increase in pain when drinking

A

Citrus drinks

60
Q

Two important complication of mumps

A

Meningits

Orchitis

61
Q

Most common cause of bronchiolitis

A

Respiratory syncytial virus

62
Q

Ribavirin can be used in infections caused by

A

Hepatitis C

Respiratory syncytial virus

63
Q

Cause of laryngotracheobronchitis

A

Parainfluenza virus

64
Q

Treatment for croup

A

Supportive (racemic epinephrine)

65
Q

Radiologic finding in croup

A

Steeple sign

66
Q

Histopathologic finding in rabies

A

Negri bodies

67
Q

Animal reservoir of SARS coronavirus

A

Horseshoe bat

68
Q

SARS coronavirus binds to these receptors in the lungs

A

ACE-2

69
Q

Breakbone fever is seen in

A

Dengue

70
Q

Vector of dengue

A

Aedes aegypti

71
Q

Most prevalent blood-borne pathogen

A

Hepatitis C

72
Q

Most common indication for liver transplant is infection with

A

Hepatitis C

73
Q

Treatment of hepatitis C infection

A

Interferon

Ribavirin

74
Q

Common location of lymphadenopathy in rubella

A

Posterior auricular

75
Q

Also known as three-day measles

A

Rubella / German measles

76
Q

Most common cardiac anomaly in congenital rubella

A

Patent ductus arteriosus

77
Q

HIV protein used for attachment to CD4

A

gp120

78
Q

gp120 and gp41 are encoded in this gene

A

env

79
Q

This HIV gene encodes the structural proteins for nucleocapsid and matrix

A

gag

80
Q

Phase of HIV infection wherein there is rapid viral replication but HIV test is negative

A

Phase 1 - Window period

81
Q

Mycobacterium avium infection, histoplasmosis, and CMV retinitis are seen at CD4 counts of less than

A

50

82
Q

Pneumocystis jiroveci pneumonia is seen at CD4 counts of less than

A

200

83
Q

The only DNA virus among the hepatitis viruses

A

Hepatitis B virus

84
Q

What is the diagnostic test of choice for influenza?

A

Reverse PCR

Microbiology and Parasitology (7 decks)

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