Virology Flashcards

0
Q

Definition of a lower resp tract infection

A

Infection of the resp tract that affects organs below the larynx

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1
Q

Common resp viruses that cause pneumonia

A
  • parainfluenza
  • RSV
  • CMV
  • adenovirus
  • measles, varicella
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2
Q

Patients at risk for serious complications from hep A

A
  • elderly
  • pregnant
  • patients with chronic liver disease
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3
Q

Contexts where hep A outbreaks tend to occur

A
  • crèche, hostels, communal gatherings
  • food assoc - spread by food handlers
  • water assoc - water contaminated with faeces
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4
Q

Types of hep that can cause chronic hep

A

B,C,D

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5
Q

Drugs used to treat chronic hep B

A
  • interferon
  • lambic using
  • emtracitabine
  • tenofovir
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6
Q

Drug used to treat HIV and HBV

A
  • tenofovir
  • nucleoside reverse transcriptase inhibitor
  • inhibits transcriptase function by chain termination when RT transcribes intermediate RNA to genomic DNA
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7
Q

Drug to treat HBV and HCV

A
  • interferon alpha
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8
Q

Markers to diagnose HCV

A
  • hep C antibody

- hep C RNA

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9
Q

In order of infectivity, viruses that are transmitted by needle stick

A
  • hep B(5-50%)
  • hep C (2%)
  • HIV (0.3%)
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10
Q

Host defences against LRTI

A
  • cough reflex
  • mucociliary clearance
  • alveolar macs
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