Viral stuff Flashcards
why do we need a new flu vaccine evry year
it changes via antigenic shift and drift
what are the differences between antigenic shift and drift
drift -> minot changes
shift -> major chages
what are the different types of flu vaccine
IM -> inactivated
intranasal -> live attenuated
what type of virus is influenza
RNA
what antivirals can be used for influenza
Oseltamivir
what are the 2 different types of antigens in influenza and what do they do
H -> attach & enter host cell
N -> release from host cell
what are the layman terms for infectious mononucleosis
glandular fever
mono
kissing disease
what is the casues of infectious mononuclerosis (glandular fever)
EBV
what are some special signs of infectiosu mononucleosis
petechiae on palate
splenomegaly
atypical lymphocytes
herterophile antibodies
macropapular & puritic rash
what are the common features of mono
sore throat
fever
lymphadenopathy
infectous mono
- what type of antibdoies are there
- what occurs on the palate
- what organ is enlarged
- what sort of rash do you get
- heterophile
- petechiae
- spleen
- macropapular & puritic
how is mono diagnosed
MOnospot test
how is mono managed
Just supportive treatment
no antivirals
what are folk with mono at risk of and what must you tell them
Splenic rupture
avoid contact sports for 8 weeks
what can EBV cause
Infectious mononuclerosis
Lymphoma
Oral hairy leukoplakia
Nasopharyngeal ca
what causes mumps
RNA para-myxo-virus
mumps
- how does it present
- time of year it’s most commmon
- how is it prevented
- is it a notifiable disease
- how is it managed
- fever, muscle pain, ear ache, pain when eating
- winter & spring
- MMR vacine
- yes
- supportive only
even though you get the MMR vaccine, how can you still get mumps
vaccine is only 80% effective
is mumps a notifiable disease
yes
what causes the ear ache and pain when eating in mumps
parotitis
how is mumps diagnosed
salivia igM
Mumps => IgM
what are some potential complicatoins of mumps
orchitis
pancreatiits
hearing loss
an increase level of anti-streptolysin O titres is a sign of…
what abx do you give
Rheumatic fever
Benzyl penicillin
whats this
what causes it
Slapped cheek syndrome (erthema infectiousm)
parovirus B19
what is the proper name for slapped cheek syndrome
erythema infectiousm
erythema infectiousm
- cause
- need to be exlcuded from school?
- treatment
- who to avoid
- parovirus B19
- no need
- just suportiv
- pregnant ladies
how would you describe the face of someone wiht ertyhema infectiousum
red hand print rash
cicrumoral pallor (pale around the mouth)
what do you do if a pregnant lady has been exposed to a kid with erythema infectiousm
check maternal IgG and IgM
what type of cancers can ebv casue
Nasopharyngeal
lymphoma
post-transplant
Hodgkins
HIV
Burkitts
