Viral stuff Flashcards

1
Q

why do we need a new flu vaccine evry year

A

it changes via antigenic shift and drift

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2
Q

what are the differences between antigenic shift and drift

A

drift -> minot changes

shift -> major chages

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3
Q

what are the different types of flu vaccine

A

IM -> inactivated

intranasal -> live attenuated

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4
Q

what type of virus is influenza

A

RNA

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5
Q

what antivirals can be used for influenza

A

Oseltamivir

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6
Q

what are the 2 different types of antigens in influenza and what do they do

A

H -> attach & enter host cell

N -> release from host cell

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7
Q

what are the layman terms for infectious mononucleosis

A

glandular fever

mono

kissing disease

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8
Q

what is the casues of infectious mononuclerosis (glandular fever)

A

EBV

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9
Q

what are some special signs of infectiosu mononucleosis

A

petechiae on palate

splenomegaly

atypical lymphocytes

herterophile antibodies

macropapular & puritic rash

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10
Q

what are the common features of mono

A

sore throat

fever

lymphadenopathy

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11
Q

infectous mono

  1. what type of antibdoies are there
  2. what occurs on the palate
  3. what organ is enlarged
  4. what sort of rash do you get
A
  1. heterophile
  2. petechiae
  3. spleen
  4. macropapular & puritic
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12
Q

how is mono diagnosed

A

MOnospot test

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13
Q

how is mono managed

A

Just supportive treatment

no antivirals

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14
Q

what are folk with mono at risk of and what must you tell them

A

Splenic rupture

avoid contact sports for 8 weeks

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15
Q

what can EBV cause

A

Infectious mononuclerosis

Lymphoma

Oral hairy leukoplakia

Nasopharyngeal ca

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16
Q

what causes mumps

A

RNA para-myxo-virus

17
Q

mumps

  1. how does it present
  2. time of year it’s most commmon
  3. how is it prevented
  4. is it a notifiable disease
  5. how is it managed
A
  1. fever, muscle pain, ear ache, pain when eating
  2. winter & spring
  3. MMR vacine
  4. yes
  5. supportive only
18
Q

even though you get the MMR vaccine, how can you still get mumps

A

vaccine is only 80% effective

19
Q

is mumps a notifiable disease

A

yes

20
Q

what causes the ear ache and pain when eating in mumps

A

parotitis

21
Q

how is mumps diagnosed

A

salivia igM

Mumps => IgM

22
Q

what are some potential complicatoins of mumps

A

orchitis

pancreatiits

hearing loss

23
Q

an increase level of anti-streptolysin O titres is a sign of…

what abx do you give

A

Rheumatic fever

Benzyl penicillin

24
Q

whats this

what causes it

A

Slapped cheek syndrome (erthema infectiousm)

parovirus B19

25
Q

what is the proper name for slapped cheek syndrome

A

erythema infectiousm

26
Q

erythema infectiousm

  1. cause
  2. need to be exlcuded from school?
  3. treatment
  4. who to avoid
A
  1. parovirus B19
  2. no need
  3. just suportiv
  4. pregnant ladies
27
Q

how would you describe the face of someone wiht ertyhema infectiousum

A

red hand print rash

cicrumoral pallor (pale around the mouth)

28
Q

what do you do if a pregnant lady has been exposed to a kid with erythema infectiousm

A

check maternal IgG and IgM

29
Q

what type of cancers can ebv casue

A

Nasopharyngeal

lymphoma

post-transplant

Hodgkins

HIV

Burkitts