Fevers & PUO

Question 1

What is the actual organism/substance that causes a fever

what are the different types & how do they work

Answer 1

PYRO-genes

Exo and endo-geneous

vasoconstriction, reducing peripheral heat loss

Question 2

what are some causes of PUO

Answer 2

Infections (e.g. TB)

Inflammaiton

Lymphoma

IE

GCA

Question 3

what are the different types of PUO

Answer 3

Classical -> normal

Noso-comial -> Hospital acuired

Neutropenic -> low neutrophil count

HIV-associated

Question 4

what tests do you do for PUO with with the following…

1. travel to tropical areas
2. heart murmurs
3. headache & jaw pain
4. heamaturia
5. IV drug users

Answer 4

1. blood culutrs & viral PCRs
2. ECHO
3. inflammatory markers & temporal artery biopsy
4. Renal USS & ANCA tests
5. HIV tesst & hep B/C serology