Vinca Alkaloids Flashcards by Andrew McCallion

Examples

Vincristine
Vinblastine
Vinorelbine

How well did you know this?

Not at all

Perfectly

MoA

Tubulin (cell spindle apparatus subunit)

Causes metaphase arrest

How well did you know this?

Not at all

Perfectly

Indications

Haematological, Lung + Breast Cancers

How well did you know this?

Not at all

Perfectly

ADR

Hair Loss
Mouth Ulcers
N+V+D
Local allergic reactions
BM suppression
Infertility
Renal/Cardiac impairment

How well did you know this?

Not at all

Perfectly

Prescribing Advice

Cancer cells may develop resistance

How well did you know this?

Not at all

Perfectly

Brainscape's Knowledge GenomeTM