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Anti-Cancer Drugs > Taxanes > Flashcards

Taxanes Flashcards

1
Q

Example

A

Paclitaxel

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2
Q

MoA

A

Satbilize GDP-bound tubular in microtubule
Promote microtubule assembly
Stop disassembly in mitosis
= Excess microtubules

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3
Q

Indications

A

Ovarian, Breast + Lung Cancer

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4
Q

ADR

A 
Hair Loss
Mouth ulcers
N+V+D
Local allergic reactions
BM Suppression
Infertility 
Renal/Cardiac impairment
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5
Q

Prescribing Advice

A

Cancer cells may develop

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Anti-Cancer Drugs (8 decks)

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