Interferons (Immunotherapy) Flashcards
1
Q
MoA
A
Interferon receptors
Agonist
Induction of interferon target genes
Immunomodulatory effects = Anti-proliferative, apoptotic, anti-angiogenic
2
Q
Indications
A
Melanoma, Renal cell cancer, HIV-related Kaposi’s Sarcoma, hairy cell leukaemia, CML + Non-Hodgkin’s Lymphoma
3
Q
ADR
A
Flu-like Sx
Fatigue
Depression