Interferons (Immunotherapy) Flashcards

1
Q

MoA

A

Interferon receptors
Agonist
Induction of interferon target genes
Immunomodulatory effects = Anti-proliferative, apoptotic, anti-angiogenic

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2
Q

Indications

A

Melanoma, Renal cell cancer, HIV-related Kaposi’s Sarcoma, hairy cell leukaemia, CML + Non-Hodgkin’s Lymphoma

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3
Q

ADR

A

Flu-like Sx
Fatigue
Depression

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