Anti-Tumour Antibiotics Flashcards

1
Q

Examples

A

Actinomycin
Mitomycin C
Bleomycin

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2
Q

MoA

A
Bind DNA at transcription initiation complex
Stop RNA formation
Cross-linking of DNA via alkylation
Induction of DNA strand breaks 
Free radical formation
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3
Q

Indications

A

Testicular + Haematological cancers

Sarcomas

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