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Anti-Cancer Drugs > Biological Chemotherapy (Monoclonal Ab) > Flashcards

Biological Chemotherapy (Monoclonal Ab) Flashcards

1
Q

Examples

A 
Rituximab
Mylotarg
Campath
Bexaar
Herceptin
Avastin
Cetixumab
Panitumab
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2
Q

MoA

A

Targets CD20 to induce apoptosis (Rituximab)
Targets Her-2 Receptor (Herceptin)
Targets VEGF - Prevents angiogenesis (Avastin)
Targets EGFR (Cetuximab + Panitumab)

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3
Q

Indications

A 
NHL = Ritxumab + Bexaar
AML = Mylotarg
CLL = Campath
Her-2 Breast Cancer = Herceptin
CRC = Avastin, Cetuximab, Panitumab
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4
Q

ADR

A

B-cell depletion, Myelotoxicity = Rituximab
Fever + chills = Avastin
Rash = Panitumab

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Anti-Cancer Drugs (8 decks)

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