VII - Other Bacteria Flashcards

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1
Q

Bacteria in undulating fever

A

Brucella abortus

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2
Q

DOC in Brucellosis

A

Doxycycline + Rifampin

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3
Q

Brucella transmission

A

contaminated dairy

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4
Q

Bacteria in Tularemia

A

Francisella tularensis

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5
Q

Reservoir of Francisella

A

Rabbits, deer, rodents

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6
Q

Tularemia transmission

A

ticks (Dermacentor)

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7
Q

DOC for Tularemia

A

Streptomycin, Gentamicin

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8
Q

Bacteria in bubonic plague

A

Yersinia pestis

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9
Q

Most virulent bacteria

A

Yersinia pestis

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10
Q

Morphology of Yersinia pestis

A

safety pin staining

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11
Q

DOC in bubonic plague

A

Streptomycin + Tetracyclin

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12
Q

Reservoir of Yersinia

A

Wild rodents

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13
Q

Clinical finding in bubonic plague

A

buboes

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14
Q

Transmitted thru animal bites, exhibit bipolar staining

A

Pasteurella multocida

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15
Q

Assay for drug resistance in Mycobacterium tuberculosis

A

Luciferase assay

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16
Q

Most imporant virulence factor in TB

A

Cord factor

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17
Q

TB virulence factor, prevents phagosome-lysosome fusion

A

Sulfatide

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18
Q

TB virulence factor, elicits delayed hypersensitivity

A

Tuberculin surface protein

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19
Q

PPD cut-off in low-risk

A

> 15mm

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20
Q

PPD cut-off in high-risk

A

> 10mm

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21
Q

PPD cut-off in HIV, AIDS, old TB, immunocompromised

A

> 5mm

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22
Q

Finding in apical TB, reactivation

A

Simon’s focus

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23
Q

Causes pulmonary disease in immunocompromised pts, CD4 <50

A

Mycobacterium avium-intracellulare complex

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24
Q

Reservoir, culture of Mycobacterium leprae

A

Armadillo

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25
Q

2 types of leprosy

A

Tuberculoid, Lepromatous

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26
Q

DOC in tuberculoid leprosy

A

Dapsone + Rifampin

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27
Q

DOC in lepromatous leprosy

A

Dapsone + Rifampin + Clofazimine

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28
Q

(+) Lepromin test in (tuberculoid? Lepromatous?)

A

Tuberculoid

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29
Q

Presents with hard swollen sinus tracts in local trauma (jaw, dental)

A

Actinomyces israelli (Actinomycosis)

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30
Q

DOC in Actinomycosis

A

Penicillin G

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31
Q

Bacteria with hyphae

A

Nocardia asteroides

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32
Q

Manifestation of Nocardia in lung and brain abscess

A

Mycetomas

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33
Q

Smallest free-living organism

A

Mycoplasma pneumoniae

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34
Q

Provides attachment for Mycoplasma

A

Toll-like receptor 2 protein

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35
Q

MCC of walking/atypical pneumonia

A

Mycoplasma pneumoniae

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36
Q

MCC infectious cause of SJS

A

Mycoplasma pneumoniae

37
Q

DOC for Mycoplasma

A

Erythromycin

38
Q

Nonulcerated ulcer, non-painful, in primary syphilis

A

Chancre

39
Q

Warty lesion of the genitals in secondary syphilis

A

Condyloma lata

40
Q

Granulomas of tertiary syphilis

A

Gummas

41
Q

Neurologic findings in tertiary syphilis

A

Tabes dorsalis, Argyll-Robertson/Prostitute pupil, dementia paralytica

42
Q

Findings in congenital syphilis

A

Saddle nose, Hutchinson triad (Hutchinson teeth, deafness, keratitis)

43
Q

Unilateral enlargement of sternoclavicular portion of clavicle

A

Higoumenakis sign, in congenital syphilis

44
Q

COD in congenital syphilis

A

Pulmonary hemorrhage

45
Q

Diagnostic of choice in primary syphilis

A

Darkfield microscopy

46
Q

Diagnostic of choice in secondary syphilis

A

RPR/VDRL

47
Q

Confirmatory test in syphilis

A

FTA-ABS

48
Q

DOC in syphilis

A

Penicillin G

49
Q

Drug reaction to Penicillin due to lysis of spirochetes

A

Jarisch-Herxheimer reaction

50
Q

Bacterial etiology of Lyme disease

A

Borrelia burgdorferi

51
Q

Largest medically-important bacteria

A

Borrelia burgdorferi

52
Q

Transmission of Lyme disease

A

Ixodes scapularis (deer tick)

53
Q

Stage 1 Lyme disease, clincal finding

A

Erythma chronicum migrans

54
Q

Stage 2 Lyme disease, clinical finding

A

AV block, Bell’s palsy

55
Q

Stage 3 Lyme disease

A

migratory polyarthritis

56
Q

DOC in Lyme disease

A

Doxycycline

57
Q

Etiology of Relapsing fever

A

Borrelia recurrentis

58
Q

DOC in relapsing fever

A

Tetracycline

59
Q

Microscopic finding is Shepherd’s crook (hook at one or both ends)

A

Leptospira interrogans

60
Q

Gold standard in diagnosis of leptospirosis

A

Lepto MAT

61
Q

2 Phases of leptospirosis

A

Acute leptospiremic phase, Immune leptospiruric phase

62
Q

Clinical findings in acute leptospiremic phase

A

Calf tenderness, conjunctivl suffusion

63
Q

Clinical fingings in immune leptospiruric phase

A

meningitis, GN, hepatic necrosis

64
Q

Xray findings in leptospirosis

A

Snowflake lesion

65
Q

DOC in leptospirosis

A

Penicillin G

66
Q

Most severe form of leptospirosis

A

Weil syndrome

67
Q

COD in Weil syndrome

A

Pulmonary hemorrhage

68
Q

Infectious form of Chlamydia trachomatis

A

Elementary body (extracellular)

69
Q

Reproductive form of Chlamydia trachomatis

A

Reticulate body (intracellular)

70
Q

MCC of STD overall

A

Chlamydia trachomatis D-K

71
Q

MCC infectious cause of blindness

A

Chlamydia trachomatis A-C (trachoma)

72
Q

Microscopic finding in trachoma

A

Halberstadter-Prowazek inclusions

73
Q

Cough in Chlamydial neonatal pneumonia

A

Staccato cough

74
Q

Etiology of lymphogranuloma venereum

A

Chlamydia trachomatis L1-L3

75
Q

(+) Frei test

A

Lymphogranuloma venereum

76
Q

Bird fancier’s disease

A

Chlamydia psittaci (psittacosis)

77
Q

DOC in chlamydia STD

A

Azithromycin

78
Q

DOC in chlamydia conjunctivitis

A

Erythromycin

79
Q

DOC in LGV

A

Doxycycline

80
Q

DOC in psittacosis

A

Azithromycin

81
Q

Rickettsial rash starting at wrist, spreads centripetal

A

Rocky mountain spotted fever

82
Q

Rickettsial rash starting at trunk, spreads centrifugal

A

Typhus

83
Q

Ricketssial disease with no rash, no vector, (-) Weil-Felix, not obligate intracellular

A

Q fever

84
Q

Cat scratch fever in immunocompetent

A

Bartonella henselae

85
Q

Etiology of Bacterial vaginosis

A

Gardnerella vaginalis

86
Q

(+) whiff test, clue cells

A

Gardnerella vaginalis

87
Q

Etiology of chancroid

A

Haemophilus ducreyi

88
Q

Etiology of Donovanosis, beefy red ulcers

A

Klebsiella granulomatis