VI - G(-) Flashcards
Morphologic appearance is kidney-bean diplococci
Neisseria meningitidis, Neisseria gonorrheae
MCC of meningitis in 2-18 yrs
Neisseria meningitidis
Rash of meningococcemia
Purpura fulminans
Most severe form of meningococcemia
Waterhouse-Friedrichsen syndrome
DOC for meninggococcemia
Penicillin G
Meningococci vaccine contains capsular polysaccharides of which strains
W135, A, C, Y
G(-) diplococci
Neisseria
G(-) maltose fermenter
Neisseria meningitidis
Frequent co-infection with N. gonorrhea
Chlamydia trachomatis
MCC of urethritis
Neisseria gonorrheae
MCC of PID
Neisseria gonorrheae
PID finding of perihepatisis with violin strings adhesion on capsule
Fitz-Hugh-Curtis Syndrome
MCC of septic arthritis in sexually active adults
Neisseria gonorrheae
DOC for gonorrheae
Ceftriaxone + Doxycycline
Etiology of ophthalgia neonatorum
Neisseria gonorrheae
Etiologic agents in subacute bacterial endocarditis, culture (-), in pre-existing heart disease
Kingela kingae, Eikenella corrodens
Confers invasiveness to Haemophilus influenza
Polyribitol phosphate (type B)
MCC of epiglottitis
Haemophilus influenzae
Presents as stridor, Steeple sign
Epiglottitis
Clinical manifestation of H. influenzae
(EMOP) Epiglottitis, Meningitis, Otitis Media, Pneumonia
DOC for H. influenzae
Ceftriaxone
Etiologic agent of whooping cough/tuspirina
Bordetella pertusis
Toxin that causes whooping in pertussis
tracheal cytotoxin
Toxin that mediates attachment of Bordetella pertussis
hemagglutinin
Most infective phase in pertusis
Catarrhal phase (1-2 weeks)
DOC for pertussis
Erythromycin
G(-) intracellular bacteria, visualized with Silver stain, grown on charcoal yeast
Legionella pneumophila
Transmission of Legionella pneumophila
Aerosol, NOT human-human
Clinical manifestation of Legionella
atypical pneumonia (hypoatremia, diarrhea)
DOC for Legionella
Azithromycin (or Erythromycin)
G(-) lactose fermenter, green sheen
Escherichia coli
E.coli pathogens
enterotoxins, pili, flagellum (H), endotoxin (O), capsule (K)
Traveler’s diarrhea
ETEC
Hemorrhagic colitis, HUS
EHEC
Watery diarrhea in infants
EPEC
Persistent diarrhea in HIV patients
EAEC
Bloody diarrhea only
EIEC
MCC of community-acequired UTI
Escherichia coli
MCC of meningitis in Philippines
Escherichia coli
2nd MCC of meningitis worldwide
Escherichia coli
DOC for E.coli UTI
Ampicillin
DOC for E.coli meningitis
3rd gen Cephalosporin
G(-) nonlactose fermenting, H2S producing, motile, oxidase (-), XLD medium
Salmonella spp.
Salmonella, enterocolitis
S. enteritidis, S. typhimurium
Salmonella, thyphoid fever
S. typhi
Salmonella, septicemia
S. choleraesuis
Typhoid fever antigen
Vi capsular antigen
Earliest culture source in typhoid
Blood
Culture source in chronic carrier, typhoid
Bile
Most consistent culture source in typhoid
Bone marrow
Week of complications (ileitis) in typhoid
Week 3
DOC for Salmonella spp.
Amoxicillin in PH, Ciprofloxacin
G(-) nonlactose fermenting, non H2S producing, nonmotile
Shigella spp.
MCC of bacillary dysentery
Group D (Shigella sonnei / Duval’s bacillus)
Most severe form of bacillary dystentery
Group A, type 1 (Shigella dysenteriae / Shiga bacillus)
DOC for Shigella
Ciprofloxacin (Nalidixic acid in IMCI)
G(-) coma-shaped, motile, oxidase-positive
Vibrio spp.
Motility of Vibrio
Shooting star
Vibrio species in human colon only
Vibrio cholerae
Enterotoxin in cholera
Choleragen
Pandemics by Vibrio caused by
Vibrio cholerae O1, El Tor
Character of stools in cholera
watery, large volumes (rice-water stools)
DOC in cholera
Tetracycline
G(-) coma-shaped, oxidase positive, microaerophilic
Campylobacter jejuni
MCC of bacterial gastroenteritis
Campylobacter jejuni
Complication of Campylobacter secondary to cross-reactivity to glycosophingolipins on surface of neural tissues
Guillain-Barre syndrome
Reactive arthritis in Campylobacter infection
Reiter’s syndrome
G(-) microaerophilic, urease(+)
Helicobacter pylori
Pathogenesis of H. pylori
Conversion of urea to ammonia by urease
Triple therapy in H. pylori
COM/A: Clarithromycin + Omeprazole + Metronidazole or Amoxicillin
Quadruple therapy in H. pylori
TOMB: Tetracycline, Omeprazole, Metronidazole, Bismuth
MCC of pneumonia in alcoholics
Klebsiella pneumoniae
Sputum in Klebsialla pneumonia
Currant jelly-like, necrotizing pneumonia
G(-) lactose fermenter, urease positive, extended spectrum B-lactamase
Klebsiella pneumoniae
G(-) bacteria responsible for struvite stones/Mg-ammonium-phosphate/Staghorn calculi
Proteus mirabilis
Pathogenesis of struvite stones
Urease converts urea in urine to ammonium
DOC in struvite UTI
TMP-SMX
G(-) oxidase(+) with pyocyanin
Pseudomonas aeruginosa
Odor of Pseudomonas
grape-like
Etiology of burn wound infections, hot tub folliculitis
Pseudomonas aeruginosa
MCC of otitis externa
Pseudomonas aeruginosa
MCC of malignant otitis externa
Pseudomonas aeruginosa
MCC of chronic suppurative otitis media
Pseudomonas aeruginosa
MCC of pneumonia in cystic fibrosis
Pseudomonas aeruginosa
Cephalosporin for Pseudomonas
Ceftazidime/Cefepime
Penicillin for Pseudomonas
Ticarcillin/Piperacillin
G(-) anaerobe, predominant anaerobe of human colon
Bacteroides fragilis
DOC in Bacteroides
Metronidazole