Via De Las Pentosas Fosfato Flashcards

1
Q

Función de la vía

A

Se genera NADPH y ribosa

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2
Q

Primera fase

A

Oxidativa
Irreversibles
Genera aNADPH

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3
Q

Segunda fase

A

No oxidativa
Genera derivados de Ribosa
Reversibles

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4
Q

En donde se encuentra

A

Hígado
Tiroides
Corteza suprarenal
Adipocitos
Eritrocitos
Testiculos
Mamá lactante

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5
Q

Substrato inicial

A

Glucosa 6 fosfato

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6
Q

Producto final

A

Ribosa 5-P, NAPH

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7
Q

Primer paso

A

Glucosa pasa a glucosa 6-fosfato

Enzima hexocinasa o glucoquinasa
Utilizan atp

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8
Q

Fase redox o oxidativa
Paso 1

A

Glucosa 6 fosfato a 6-fosfogluconato

Cataliza por glucosa 6 fosfato deshidrogenasa
Se produce el primer NADH
Se agrega agua

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9
Q

Fase redox o oxidativa
Paso 2

A

6-fosfogluconato a rubulosa 5-fosfato

Oír 6-fosfogluconato deshidrogenasa
Se genes segundo NADH
DESCARBOXILACION

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10
Q

Fase no oxidativa
Paso 1

A

3 moléculas de ribulosa 5-fosfato

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11
Q

Primera molécula de ribulosa 5P

A

Pasa a xilulosa por la epimerasa
Pasa a Gliceraldehido 3P por la transcetolasa
Pasa a fructosa por la transaldolasa

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12
Q

Segunda ribulosa 5P

A

Pasa a Ribosa 5P por la isomerasa
Pasa a sedoheptulosa 7P por transcetolosa
Pasa a eritrosa 4P por la transaldolasa
Pasa a fructosa-6P por transcetolasa

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13
Q

Tercera ribulosa 5P

A

Ribulosa 5-P pasa a xilulosa-5P por la epimerasa
Pasa a Gliceraldehido por la transcetolasa

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