Veterinary Nutraceuticals Flashcards

1
Q

Nutraceutical

A

Oral compounds, neither drugs nor nutrients

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2
Q

Nutraceuticals are regulated by

A

FDA - only when a product becomes unsafe or is associated with a label that claims a drug use

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3
Q

Food

A

Article used for food or drink, provides taste, aroma or nutritive value. Primary role of nutrition is prevention of diseases.

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4
Q

Drug

A

Any substance, food or non-food used to treat, mitigate or prevent disease

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5
Q

Feed Additive

A

Product not considered GRAS - must undergo a pre-market approval process

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6
Q

Federal Food, Drug and Cosmetic Act (FDAC)

A

Created by FDA

Ensure safety of human drugs - defined foods, drugs and feed additives

Assures drug efficacy in mission of FDA, formation of the Center of Veterinary Medicine (CVM)

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7
Q

FDA Amendments Act (FDAAA)

A

Requires FDA to set ingredient definitions and processing standards for petfoods, modifying petfood labels and creating a food adulteration incident reporting system

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8
Q

FDA and AAFCO Memorandum of Understanding (MOU)

A

FDA has assumed greater authority over the AAFCO feed ingredient definition process

AAFCO is developing regulations to institute good manufacturing practices for all animal feeds

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9
Q

Dietary Supplement Health and Education Act (DSHEA)

A

Effectively restrict FDAs ability to regulate dietary supplements

Legally defines a dietary supplement

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10
Q

Association of American Feed Control Officials (AAFCO)

A

Non regulatory organization of federal and state feed officials

Voluntary guidelines and not all states abide by them

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11
Q

Sources of N-6 PUFA

A

Corn, Cottonseed, Peanut, Safflower, Sunflower, Olive, Soybean, and Canola Oils

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12
Q

Sources of N-3 PUFA

A

Fish Oil, Flaxseed Oil, Canola Oil, Soybean Oil

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13
Q

Adverse reactions to PUFA supplementation

A
Bleeding dyscrasias
Lipid Peroxidation
Immunosuppression
Vitamin E Deficiency 
Competition with other PUFA
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14
Q

Glucosamine (GS)

A

Aminomonocaccharide made from glucose

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15
Q

Chondrotin Sulfate (CDS)

A

Mucopolysaccharide found in mammalian cartilage

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16
Q

Describe the structure of cartilage

A

Glycosaminoglycan “Bristles consisting of Chondroitin sulphate chains and keratan sulphate chains all of which make up aggrecan protein “core”

17
Q

Are GS and CDS absorbed?

A

Oral GS and CDS seem to be absorbed in the GIT of dogs -both show higher concentrations in joints than in plasma after prolonged oral administration

18
Q

Four morphological zones of cartilage

A

Superficial Zone
Intermediate/Middle Zone
Deep Zone
Zone of Calcified Cartilage