Vet Sci final Flashcards
Define dosage and dose. List dosage intervals
Dosage- Amount of drug/unit of body weight (mg/kg), Dose- Amount of drug given at one time (cc/ml). SID, BID, TID, QID, EOD, PRN, Q2H
List some factors that may require an adjustment of dosage or meds? What are some preexisting conditions that may effect the dosage or type of meds used?
Adjustment- breed, species, pregnancy (gender), age, preexisting conditions
Preexisting conditions- renal/liver failure, seizures, shock, drug interactions
What are some potential toxicities of administered drugs?
Allergic reaction, inappropriate species, inappropriate amount or frequancy, inappropriate route of administration
What are the four classic steps in drug movement in the body? What makes up the first phase of biphasic drug distribution? What makes up the second phase?
Absorption, distribution, biotransformation, elimination.
First phase- Absorption, distribution
Second phase- Biotransformation, ditribution
List the routes for administration of medications from fastest to slowest rate of absorbtion
Fastest- IV, IO IC
Intermediate- Im, Sub-Q, IP, ET
Slowest- PO
What is a lipophilic drug? What is a hydrophilic drug? What routes for admin of meds would each type be likely to be used?
Lipophilic- Drugs that disolve in oil. PO
Hydrophili- Drugs that disolve in water. IV, SQ, IM
What is the primary site for bitransformation of drugs in the body? What are the secondary sites? What is the primary site for excretion of drugs in the body? What are the secondary sites?
Primary site- Liver
Secondary site- Lungs, skin, intestinal tract
Primary site- Kidneys
Secondary site- liver, lungs, sweat, mammary glands
What are the 2 major categories of routes for administration of medications? List the routes for administration in each category
Enteral (involves GI tract), Parenteral (bypasses GI, topical or injectable)
What are the advantages for using enteral routes of administration? What are the disadvantages?
non-envassive, generally safe, painless, economical, no training required, decreased risk of infection. Increased risk of aspiration or vomiting, diarrhea, possible injury to pt or administer, accuracy of dose
List the different type of oral meds. What are the indications for the oral route? What are contraindications for the oral route?
pils, liquids, powders granules, paste.
Indications- Treating specific GI disorder, when immediate absorption is unnecessary, when dispensing home meds
Conraindications- V/D, when rapid absorption is needed, when there is possible interference w/ other drugs
List the indications for use of an orogastric tube. What are some complications that may occure when using an orogastric tube? Describe placment of an orogastric tube in an adult. List some things one may do to check for proper placment. Describe differences in placement in puppy or kitten
Nutritional support in anorexic pt, admin of a medication, admin of raiographic contrast material, decompressionof stomach, stomach lavage, dislodging a foreign body. Misplacment of the tube, esophageal or gastric injuries. Measure and mark the tube, use speculum/roll of tape, lube tube, administer meds. Swallowing good, seeing the tube go down the esophagus, feeling 2 tubes, listen & smell, coughing good, radiograph best indication. Dog tip of nose to last rib, cat tip of nose to 10th or 11th rib. Use a red rubber catheter with puppies and kittens
What are some indications of a nasogastric tube? What are some coplications?
Longer term acces to stomach than orogastric, nutritional support , decompression of the stomach, administering meds. misplacment of the tube (aspiration pneumonia), epistaxis, esophegeal or gastric injuries, smaller width & tube be mindfull.
What are some indications for use of a surgically placed feeding tube? List some complications that may occur when placing a feeding tube
Prolonged nutrintional support, GI injury. Surgery, infection, dislodgment of tube, extensive aftercare
What are 3 indications for use of an enema? What complication may occur when administering an enema?
Relief of constipation, evacuation of the distal colon (diagnostic studies, surgery), admin of meds. Rectal trauma
Describe the technique of applying topical medications to the skin. What precautions must be taken? List some drugs that are absorbed systemically through the skin
Wear gloves or use applicator or both, cover site if needed or use E-collar to prevent licking. Nitroglycerin, prednisolone, flea control, DMSO (dimethyl sulfoxide), analgesics (fentanyl patches)
What are some complications that may occur when giving injections?
Hemorrhage or hematoma at the site, abscess, granuloma (area of inflammed tissue), local irritation, tissue necrosis due to extra vascular deposit of an IV drug
What are the three common sites for sub-Q injections? List some meds that cannot be administered sub-Q? why? What route of admin is used and where on the body are cats vaccinated? why?
Scruff, lateral thorax, flank. Whole blood, hypertonic solutions ( 50% dextrose, 7.2% saline), oil based meds (can form granulomas, don’t dissolve). SQ and always given in distal limb because cats are prone to getting sarcomas which may have to be removed
List the 4 injection sitesused on small animals
Lumbar, quadriceps, hamstrings, gluteals
List the IO injection sites. List some indications for IO injections. List some contraindications when giving IO injections. List some drugs and fluids that may be given by IO injections
Tibial crest, trocantric fossa, wing of the illium, greater tubercle of humerus. Rapid admin of fluids or meds, when cetral or peripheral vein is unavailable (shock), when vein is to small to cath (neo, birds). Endotoxic pt (ostyomylitis), placement in certain pneumatic bones of birds, placement in fractured or previously fractured bone, placement over abcess. If it can be given IV it can be given IO.
List some theraputic indications for IP injections. List a diagnostic indacation. What are some complications that may occur when administering IP injections?
Theraputic-Fluid therapy (neo or very small animals), peritoneal lavage, peritoneal dialysis (renal disease), euthanasia (less than 15 LBs or exotics)
Diagnostic- Evaluation of peritoneal fluid, collections for culture/sensitivity
Infection, pain, local irritation, chemical peritonitis, fibrous tissue and adhesions in abdominal cavity, perferation of abdominal organ, hemorrhage, respiratory distress, to large of an injection
What is an indication for subconjunctival injection? What are 3 complications when administering? Described the technique used?
Medicating the globe of the eye usually in bovines. Irritations of the surrounding tissues, infection, perferation into the interior of the eye. Needle is placed uner the bulbar conjunctiva, 25-27 guage needle visualize needle inserting into conjunctiva and will see a bleb of medication
What are some indications for intranasal? List some vaccinations givin intranasal? what are some drugs given IN?
vaccinations (bordetella, strangles) and meds (O2, epi).
What are some indications for IC? What are some complications that may occur when administering IC injections? Describe the technique.
Admin of meds in an emergency, euthanasia, collection of blood. Trauma to the heart and lungs, irritation to the myocardium. Right lateral recumbancy, between 5th and 6th inercostal space, palpate heart beat first