vasopressin anatomy and physiology

Question 1

when vasopressin is released, it binds to G-coupled receptors around the body to display its affects, what are these called and where are they located?

Answer 1

V1a - vasculature - aortic arch and carotid sinus - vasoconstriction
V2 - renal collecting tubules - reabsorption of water
V1b - pituitary - ACTH release to inc stress repsonse

Question 2

name the receptors which monitor the body and stimulate vasopressin release

Answer 2

osmoreceptors in hypothalamus - day to day

baroreceptors in brainstem and great vessels - emergency

Question 3

where is vasopressin synthesised and released?

Answer 3

synthesisied - hypothalamus
released - posterior pituitary

Question 4

what hormones are released by the posterior pituitary?

Answer 4

oxytocin and vasopressin

Question 5

how and when would vasopressin be inhibited?

Answer 5

• low plasma osmolality (more water) - osmoreceptors sense this and inhibit ADH
• high blood pressure - baroreceptors - reduce ADH

Question 6

when is vasopressin released

Answer 6

• increase is plasma osmolality (less water)
• decrease in blood pressure