Vasoactive meds Flashcards
Esmolol dose
0.2 - 0.5 mg/kg
Esmolol onset
1 - 2 minutes
Esmolol peak
5 minutes
Esmolol duration
10 - 30 minutes
Esmolol MOA
selective beta-1 antagonist
Esmolol metabolism
plasma esterase hydrolysis
Labetalol dose
0.25 mg/kg
Labetalol onset
2 - 5 minutes
Labetalol peak
5 - 15 minutes
Labetalol duration
2 - 4 hours
Labetalol MOA
alpha-1 and beta-1+2 antagonist
Labetalol metabolism
hepatic metabolism
Hydralazine dose
5 - 20 mg
Hydralazine onset
5 - 10 minutes
Hydralazine duration
2 - 4 hours
Hydralazine MOA
lowers blood pressure by direct relaxation of vascular smooth muscle
(interferes with the calcium movements within the vascular smooth muscle that are responsible for initiating or maintaining the contractile state)
Hydralazine metabolism
hepatic metabolism