Sympathomiometics onset/peak/duration/receptor site stimulation Flashcards

1
Q

Ephedrine dose?

A

2.5-10 mg

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2
Q

Ephedrine onset?

A

Less than 1 min

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3
Q

Ephedrine peak?

A

2-5 minutes

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4
Q

Ephedrine duration?

A

10-60 minutes

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6
Q

Ephedrine is alpha 1, alpha 2, beta 1, beta 2 agonist?

A

primarily indirect alpha 1 and beta 1

small amount of direct agonism as well

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7
Q

Phenylephrine dose?

A

40-100 mcg

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8
Q

Phenylephrine onset?

A

Less than 1 minute

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9
Q

Phenylephrine peak?

A

1 minute

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10
Q

Phenylephrine duration?

A

15-30 minutes

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11
Q

Phenylephrine is an alpha 1, alpha 2, beta 1, beta 2 agonist?

A

Alpha 1

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12
Q

Epinephrine dose?

A

2-20 mcg/min

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13
Q

Epinephrine onset?

A

30 seconds

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14
Q

Epinephrine peak?

A

3 minutes

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15
Q

Epinephrine duration?

A

10 minutes

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16
Q

Alpha 1 stimulation causes?

A

Increase inotrophy and vasoconstriction

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17
Q

Alpha 2 stimulation causes?

A

Vasodilation due to CNS presynaptic inhibition of norepinephrine

18
Q

Beta 1 stimulation causes?

A

Increase inotrophy, chronotrophy, and dromptrophy

19
Q

Beta 2 stimulation causes?

A

Increase inotrophy, chronotrophy, vascular dilation, and bronchial dilation

20
Q

DA1 stimulation causes?

A

Vasodilation

21
Q

DA2 stimulation causes?

A

Inhibition of norepinephrine release

22
Q

Epinephrine stimulation causes alpha 1, alpha 2, beta 1, beta 2 agonist?

A

All of the above

23
Q

Epinephrine Metabolism?

A

Monoamine Oxidase

24
Q

Phenylephrine Metabolism?

A

Monoamine Oxidase

25
Q

Ephedrine Metabolism?

A

Hepatic with Renal Elimination

25
Q

Ephedrine max dose?

A

50 mg