vasculitis

Question 1

female
unilateral headache, jaw claudication
blindness

Answer 1

temporal arteritis

focal granulomatous inflammation
increased ESR

Question 2

asian female
weak upper extremity pulses
fevers, NS, arthritis, myalgias, skin nodules
granulomatous thickening of aortic arch

Answer 2

takayasu’s arteritis

Question 3

HBV positive
fever, weight loss, malaise, headache
abdominal pain, melena,
HTN, neurodysfunction

Answer 3

polyarteritis nodosa

immune complex emdiated
spares pulm arteries
transmural with fibrinoid necrosis
multiple aneurysms and constructions on arteriogram

Question 4

child with strawberry tongue

fever, lymphadenitis, conjunctivitis, hand foot erythema

Answer 4

kawasaki disease

look for coronary aneurysms

Question 5

smokers
autoamputation of digits
Reynaud’s

Answer 5

Buerger’s disease

segmental thrombosing vasculitis

Question 6

palpable purpura
pauci immune glomerulonephritis (negative IF)
palpable purpura
no granulomas
pos pANCA

Answer 6

microscopic polyangiitis

Question 7

perforation of nasal septum, chronic sinusitis, otitis media, mastoiditis

hemoptysis, cough, dyspnea

hematuria, red cell casts

Answer 7

wegner’s granulomatosis
focal necrotizing vasculitis
necrotizing granuloma in the lung and upper airway
necrotizing glomerulonephritis

cANCA
CXR: large nodular densities

Question 8

asthma
sinusitis
palpable purpura
peripehral neuropathy

Answer 8

churg strauss syndrome

granulomatous vasculitis with eosinophilia

pANCA

Question 9

child with recent URI
palpable purpura, arthralgia
abdominal pain, melena

Answer 9

Henoch Schonlein purpura

IgA immune complex
associated with IgA nephropathy

Question 10

port wine stain on gace
intracerebral AVM
seizures
early onset glaucoma

Answer 10

Sturge weber disease