HIV/chemo meds Flashcards

1
Q

enfuvirtide

A

HIV fusion inhibitor

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2
Q

-navir

A

protease (pol gene) inhibitor

prevents maturation of new viruses

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3
Q

-vir-

A

non nucleoside RT inhibitor

does not require phosphorylation to be active

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4
Q

Raltegravir

A

integrase inhibitor

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5
Q

toxicity of raltegravir

A

hypercholesterolemia

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6
Q

protease inhibitors toxicity

A

hyperglycemia, GI intolerance, lipodystrophy

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7
Q

nucleoside RT inhibitor toxicity

A

bone marrow supression

peripheral neuropathy

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8
Q

med for HIV in pregnancy to reduce transmission

A

Zidovudine (ZDV)

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9
Q

med to reduce methotrexate toxicity

A

folinic acid (leucovorin)

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10
Q

med for 5-fluorouracil overdose

A

thymidine

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11
Q

med to prevent cardiotoxicity with doxorubicin

A

Dexrazoxane

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12
Q

med to reduce toxicity in cyclophosphamide

A

mensa

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