Variola virus Flashcards
1
Q
Viral family and properties
A
Poxviridae
- Enveloped
- Double stranded
- Linear
- Replicates in cytoplasm
2
Q
Shape
A
Brick-shaped
3
Q
Disease caused
- Disease
- Incubation period
- Manifestations
A
- Disease
- Smallpox
- Incubation period
- 7 to 14 days
- Manifestations
- Prodrome of fever and malaise followed by centrifugal rash
- Lesions with same stage of development
4
Q
Classic smallpox lesions
A
Deep-seated, firm/hard, round well-circumscribed vesicles or pustules; as they evolve, lesions may become umbilicated or confluent
5
Q
Histopath finding
A
- Guarnieri bodies
- Intracytoplasmic eosinophilic inclusions
