RSV

Question 1

Viral family and properties

Answer 1

• Strand
  
  • SS
• Polarity
  
  • Negative sense
• Envelope
  
  • Yes
• Structure
  
  • Helical

Question 2

Why is it named so?

Answer 2

Fusion protein causes cells to fuse, forming multinucleated giant cells (syncytia)

Question 3

Envelope proteins

Answer 3

Only fusion proteins

Question 4

Host range

Answer 4

Humans only

Question 5

Disease (s) caused

Answer 5

• Bronchiolitis in babies
• Viral pneumonia

Question 6

Treatment of bronchiolitis

Answer 6

Ribavirin (used only for high risk of severe disease like prematurity)

• Memory aid:*
• _R_ibavirin – _R_SV

Question 7

Prevents pneumonia caused by RSV infection in premature infants

Answer 7

Palivizumab

• Memory aid:*
• _P_alivizumab for _P_aramyxovirus (RSV) _P_rophylaxis in _P_rimies

Question 8

Palivizumab description and action

Answer 8

Monoclonal antibody against F protein