Vancomycin Flashcards
1
Q
Is vancomycin bactericidal or static?
A
bactericidal
2
Q
What does vancomycin bind to?
A
D-ala-D-ala of peptidoglycan
3
Q
what is vancomycin active against
A
gram positive cocci and gram positive bacilli only
MRSA organisms
4
Q
When is vancomycin given PO?
A
C. Diff
5
Q
Half life of vancomycin
A
6 hours
6
Q
Main ADE of vancomycin
A
red man syndrome or red neck syndrome when infused too rapidly
7
Q
Vancomycin dosing
A
avoid exceeding 2g/dose
trough levels should be greater than 10 mg/L
more complicated infections require troughs of 15-20 mg/L
8
Q
DOC vancomycin
A
all MRSA or empiric MRSA
non severe and severe C. diff (oral therapy)
