Chloramphenicol Flashcards

1
Q

Chloramphicol MOA

A

binds to 50S

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2
Q

Is chloramphenicol bacteriostatic or bactericidal

A

Bacteriostatic

Bactericidal for a few organisms

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3
Q

How is chloramphenicol metabolized

A

metabolized in liver via reduction and conjugation with glucuronic acid

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4
Q

Main ADE chloramphenicol

A

Aplastic anemia
Gray baby syndrome (neonates don’t have glucuronide)

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