Chloramphenicol Flashcards
1
Q
Chloramphicol MOA
A
binds to 50S
2
Q
Is chloramphenicol bacteriostatic or bactericidal
A
Bacteriostatic
Bactericidal for a few organisms
3
Q
How is chloramphenicol metabolized
A
metabolized in liver via reduction and conjugation with glucuronic acid
4
Q
Main ADE chloramphenicol
A
Aplastic anemia
Gray baby syndrome (neonates don’t have glucuronide)