Valvular Heart Disease Flashcards
What are the 2 AV valves?
- Tricuspid Valve
- - Mitral valve
How many leaflets does tricuspid valve have and where are they attached?
- 3 leaflets
- - Papillary attachments on septum and moderator bands
How many leaflets does mitral valve have and where are they attached?
- 2 leaflets
- - Smoother attachments and not attached to septum
What are the 2 determinants of coronary perfusion?
- -Supply
- -Demand
What determines of supply?
CPP
HR
PaO2
Coronary artery diameter
What determines demand ?
Myocardial O2 consumption HR LV wall tension Contractility Conduction Relaxation
What is the venous drainage of the heart?
Coronary sinus
Where is the coronary sinus located?
Just above the Tricuspid valve
What is known as the pressure gradient that drives coronary blood pressure
Coronary perfusion pressure (CPP)
CPP =
Aortic diastolic - LVEDP
CPP is altered by what?
Decrease in aortic pressure
Increase in LVEDP
Increase in HR
What is the average adults coronary blood flow at rest?
250 mL
During what phase does isovolumetric contraction occur?
Systole
What must occur for ejection to take place?
When pressure in LV has been achieved and overcomes SVR to open Aortic valve thus pushing blood forward
The gradient across what valve is the difference of pressure between LV and systolic BP?
Aortic valve
Aortic stenosis will do what to the gradient across the valve during ejection?
Increase the gradient