Anesthesia for Neurosurgery Flashcards
During all neurosurgery cases, how will the head be in relation to anesthesia?
90* away from you
How many fingers should you leave between the mandible and sternum and/or clavicle to ensure proper venous drainage?
2 fingers to avoid kinking of jugular veins
Generally speaking, the tube goes too deep or becomes too shallow after positioning?
Too deep
With C spine flexion, where does the tip of ETT migrate to?
Caudally, or towards carina
causes endobronchial intubation
With C spine extension and/or rotation, where does the tip of ETT migrate to?
Cranially
closer to the vocal chords so could extubate
What are some of the rules concerning blood loss in neurosurgery?
- Blood loss difficult to estimate
- - Can lose lots of blood during closing
With IV fluids in neurosurgery, what must be taken into account?
- -Minimal third spacing
- Minimal evaporation
- Only give enough to maintain cardiac stability
- Avoid hyperglycemia
- Avoid hyper/hypo natremia
What are the two main diuretics that are used to decrease the brain’s water content?
Mannitol
Lasix
Of the hyper and hypo natremia (which are things to avoid during neurosurgery) which is the detrimental to the patient?
Hyponatremia
(water movement in/out of the brain is controlled by Na shifts, hyponatremia causes large amounts to enter, thus resulting in brain edema)
The brain looks at what aspect of IV fluids to determine effect?
Osmolarity
brain does not care about the oncotic pressure of fluids
What is the normal value for osmolarity of human plasma?
295 mOsm / L
What is the IV fluid we give that is 273 mOsm / L ?
Lactated ringers
Normal saline has what osmolarity?
308 mOsm / L
20% mannitol has what osmolarity?
1098 mOsm / L
What is the IV fluid we give that is 290 mOsm / L ?
Albumin
Is brain tissue sensitive to pain?
NO
Because brain tissue is not sensitive to pain, when are the only times that anesthesia needs to be deep?
Opening and closing
Ideally, the patient needs to be fully awake and full consciousness how long after closing of tissue?
20-30 min
What is CBF?
Cerebral blood flow
CBF accounts for how much of CO?
20%
How much does average human brain weigh?
1500 grams
What is the average CBF of an adult?
40-50 ml/100gram/minute
What is known as critical CBF?
18 mL / 100 gm
What percentage of CBF does grey matter receive?
White matter?
G M: 80%
W M: 20%
What is the new target for EtCO2 ?
Low 30’s
Between what MAP values ensures the brain is adequately perfused?
50 - 150 mmHg
For the normal autoregulatory curve associated with MAP and CBF, what causes a right shift?
Choric hypertension
For the normal autoregulatory curve associated with MAP and CBF, what causes a left shift?
Vasodilators such as inhaled anesthetics
What 2 types of ischemia can occur in brain?
Global
Focal
What is known to cause global ischemia?
- Cardiac arrest
- Severe hypotension
- Hypoxia (normal BP but without O2
How is focal ischemia defined or described?
- Temporary or permanent
- - Partial or complete arterial obstruction
A stroke is a kind of what focal ischemia?
Permanent
A TIA is a kind of what focal ischemia?
Temporary
What is known to cause focal ischemia?
- Stenosis
- Vasospasm
- Embolus
- Clip
What is the best inhaled anesthetic because it decreases CMRO2 while not affecting CBF?
Isoflurane
Halothane used to be used as an inhaled anesthetic until it was found to have what effect?
Large increase in CBF that caused brain to become congested and full
What is the only IV drug given that decreases CMRO2 but increases CBF?
Ketamine
so do use this drug during brain surgery
When treating a hypertensive patient during neurosurgery, what is best drug to use?
Labetolol
When treating a hypertensive patient during neurosurgery, what 2 drugs do you not want to use?
Nitroglycerine
Nitroprusside
Both increase ICP - CBF ratio
What is ICP?
Intracranial pressure
What is a normal ICP?
10 - 15 mmHg
What is the reference point for measurement of ICP?
Tragus of ear
Moderately increased ICP is what?
20-40 mmHg