Valve Disease (Newman) Flashcards

1
Q

2 causes of endocarditis

A

bugs in blood and diseased valve

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2
Q

What determines the integrity of the valves?

A

leaflets/cusps
support network
cardiac chambers, great vessels

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3
Q

a narrowing of an orifice, lumen

A

stenosis

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4
Q

leakage upstream

A

regurgitation

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5
Q

What the size diff of healthy and stenotic valve?

A

3 cm vs 0.5 cm

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6
Q

in what valve does regurgication happen most common?

A

aorta (in diastole)&raquo_space; mitral/left ventricle (in systole)

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7
Q

What is the cardiac adaptation to a stenotic valve?

Does a stenotic valve cause a pressure or volume overload?

A

inc thickness of wall = concentric hypertrophy

pressure overload due to inc pressure upstream

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8
Q

What is the cardiac adaptation to regurgitation?

Does a regurgitation cause an pressure or volume overload?

A

eccentric hypertrophy (enlarged chamber inc mass but normal thickness)

= heart dialtes without getting thicker!!
(volume overload bc volume increases upstream)

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9
Q

What is the thickness of the inter-ventricular septum?

A

1 cm

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10
Q

loud murmur without hypertrophy (eccentric)

A

acute regurgitation

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11
Q

What causes acute regurg? (3)

A

ischemia, infection, dissection

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12
Q
heart failure (PND, edema, JVD)
chest pain
syncope
arrhymias
** could be asymptomatic
A

acute regurgitation

chest pain (angina)

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13
Q

Where on the chest would you hear mitral regurg

A

right under left nipple

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14
Q

mitral regurg murmur is heard during _____

A

systolic murmur

lub –fhh–dub

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15
Q

aortic regurg murmur is heard during _____

A

diastolic murmur

lub-dub-fhh

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16
Q

Where on the chest would you hear aortic regurg?

A

under right clavicle

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17
Q

aortic stenosis murmur is heard during _____

A

Systole

lub-ugh-dub (cough sound)

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18
Q

in mitral stenosis the first heart sound is

A

louder

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19
Q

how must a pt be positioned? WHat part of hand do you use to feel for it?

A

left lateral dequibitis

interphalngeal joints

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20
Q

Where will PMI be felt with eccentric hypertrophy?

A

axilla

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21
Q

What should the size of the PMI be normally? pathologic?

A

size of dime–> quarter

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22
Q

concentric hypertrophy is a risk factor for …

A

CAD

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23
Q

the gradient

A

?

left ventricle pressure < aorta

24
Q

to determine the severity of the stenosis you must know…

A

gradient

CO (or Q)

25
inflammation, scarring of leaflets, chordae, and papillary muscles, frequent calcification
mitral stenosis
26
Clinical pres: | dyspnea, RHF, thrombi
mitral stenosis
27
HTN: left atrium > pulmonary bed > right heart
mitral stenosis
28
pulmonary artery catheter measures
left ventricular pressure?
29
disease affecting: supporting valve structures leaflets dilation of left atria
mitral regurg
30
loud first heart sound
mitral stenosis
31
what is the most common cause of mitral regurg?
mitral prolapse
32
leaflets replaced by myxomatous tissue
mitral valve prolapse --> mitral regurg
33
eccentric hypertrophy is the result of
Chronic mitral regurg
34
inc preload with dec afterload
mitral regurg
35
What are the 2 most common causes of mitral regurg?
infection (endocarditis) | ischemia (MI)
36
loud murmus, pulmonary edema, without enlarged ventricle or atia
acute mitral regurg
37
hwo is accute and chronic regurg diff?
lack of hypertrophy = acute
38
lub- ugh -dub heard under right clavicle
aortic stenosis
39
tardus
delayed arterial pressure (stays a little longer on your finger)
40
parvus
weakened arterial pulse
41
concentric hypertrophy + tardus + parvus
aortic stenosis
42
angina syncope HF sudden death
arotyic stenossi
43
lub-dub-shh under right clavicle
aortic regurg
44
wide pulse pressure
chronic aortic regurg
45
bacteremia + disease valve (or lesion)
2 requirements for endocaditis
46
combo of platelets + fibrin + bugs + RBCs and WBCs
vegetation
47
valve destruction -->
acute regurg
48
complications of infective endocarditis
valve destruction --> acute regurg embolization immunologic phenomena
49
What are the 3 indications for surgery in IE
1. heart failure unresponsive to medical management 2. uncontrolled infection 3. recurrent major emboli
50
Turbulent flow is indicative of...
stenosis
51
Inappropriate timing is indicative of...
regurgitation
52
Severity of stenosis is determined by:
pressure gradient | CO
53
In mitral stenosis, the severity is proportional to
HR
54
SIgns of aortic regurg
widened pulse pressure | head bobbing
55
Endocarditis requires:
bacteremia | diseased valves