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Molecular Basis Of Disease/ Microbiology And Immunology > Vaccines - Bacterial And Viral > Flashcards

Vaccines - Bacterial And Viral Flashcards

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1
Q

What vaccines do you get at 8 weeks?

A

6-in-1 virus
Rotavirus
MenB

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2
Q

What vaccines do you get at 12 weeks?

A

6-in-1
Pneumococcal
Rotavirus

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3
Q

What vaccines do you get at 16 weeks?

A

6-in-1

MenB

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4
Q

What vaccines do you get at 1 year?

A

Hib/MenC
MMR
Pneumococcal
MenB

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5
Q

What vaccines do you get at 2-10 years?

A

Flu

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6
Q

What vaccines do you get at 3 years and 4 months?

A

MMR

4-in-1 pre-school booster

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7
Q

What vaccines do you get at 12-13 years?

A

HPV

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8
Q

What vaccines do you get at 14 years?

A

3-in-1 teenage booster

MenACWY

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9
Q

What does the 6-in-1 vaccine contain?

A 
Diphtheria
Tetanus
HepB
Pertussis
Polio
Haemophilus influenza B
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10
Q

In the 6-in-1 vaccine, which are toxoid based?

A

Diphtheria
Tetanus
Pertussis

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11
Q

In the 6-in-1 vaccine, which are inactivated?

A

Polio

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12
Q

In the 6-in-1 vaccine, which are a recombinant subunit?

A

HepB

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13
Q

In the 6-in-1 vaccine, which are conjugated?

A

Hib

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14
Q

In the 6-in-1 vaccine, which are oral live?

A

Rotavirus

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15
Q

Which vaccines do you get at 65 years?

A

Pneumococcal

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16
Q

Which vaccines do you get at 65 years+?

A

Flu

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17
Q

Which vaccines do you get at 70 years?

A

Shingles

18
Q

What vaccines do pregnant women get?

A

Flu vaccine and pertussis

19
Q

What are the two versions of the shingles vaccine?

A

Live attenuated and recombinant

20
Q

What type of pathogen in neisseria meningitidis?

A

Gram negative bacteria

21
Q

What does neisseria meningitidis cause?

A

Meningitis, sepsis etc

22
Q

Why was the menC dose at four months dropped in 2013?

A

MenC incidence had fallen very significantly in the community

23
Q

Why was the menC vaccine replaced with the MenACWY vaccine in 2015?

A

To offer protection against four strains of meningococcal disease

24
Q

What is the Hib vaccine made up of?

A

Type b capsule polysaccharide linked to conjugate either diphtheria or tetanus toxoids or meningococcal outer membrane proteins

25
Q

What is the diphtheria vaccine made up of?

A

Toxoid combined with aluminium salt adjuvant

26
Q

What is the difference between the DTaP and dTaP vaccine?

A

D = higher amount of toxoid

27
Q

Which vaccines are contained within the DTaP vaccine?

A

Diphtheria, tetanus and pertussis

28
Q

What is the tetanus vaccine made up of?

A

Toxoid combined with aluminium salt adjuvant

29
Q

What does the pertussis vaccine prevent against?

A

Whooping cough

30
Q

What is the pertussis vaccine made up of?

A

Acellular - containing the toxoid,filamentous haemagglutinin and pertacin

31
Q

What is the function of filamentous haemagglutinin and pertacin in the pertussis vaccine?

A

Promotes adhesion to cells

32
Q

What is the aim of the influenza vaccine?

A

To protect those who are at most risk of serious illness or death should they develop it and to reduce circulation of the virus

33
Q

Who gets the influenza vaccine?

A 
65yrs+ 
6 months+ in a clinical risk group
People in long-stay residential facilities
Elderly or disabled carers
People who live with immunocompromised
Health and social care workers
Pregnant women 
Those who work with poultry 
2-10yrs
34
Q

What is the flu vaccine made up of?

A

Quadrivalent inactivated (two subtypes of fluA and two of fluB)

35
Q

What does pneumococcal infection cause?

A 
Sinusitis
Meningitis
Otitis media
Pneumonia 
Peritonitis
Soft tissue infection
Arthritis
36
Q

What is the pneumococcus vaccine made up of?

A

Polysaccharides from the 13 most common capsule types

Conjugated to diphtheria toxoid

37
Q

What is the vaccine against human papilloma virus called?

A

Gardasil

38
Q

What does Gardasil protect against?

A

HPV serotypes 6, 11, 16 and 18

39
Q

What is a disease of the 8th day?

A

Infection of the umbilical cord -> disease manifestation on the 8th day of life

40
Q

How do you protect against neonatal tetanus?

A

Vaccinate mother late in pregnancy -> lots of maternal IgG in the neonate

41
Q

What is the vaccine against TB called?

A

BCG

42
Q

What type of vaccine is BCG?

A

live attenuated

Molecular Basis Of Disease/ Microbiology And Immunology (57 decks)

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